Migrating Schwann cells direct axon regeneration within the peripheral nerve bridge
Q Min, DB Parkinson, XP Dun - Glia, 2021 - Wiley Online Library
Schwann cells within the peripheral nervous system possess a remarkable regenerative
potential. Current research shows that peripheral nerve‐associated Schwann cells possess …
potential. Current research shows that peripheral nerve‐associated Schwann cells possess …
Schwann cells: development and role in nerve repair
KR Jessen, R Mirsky, AC Lloyd - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Schwann cells develop from the neural crest in a well-defined sequence of events. This
involves the formation of the Schwann cell precursor and immature Schwann cells, followed …
involves the formation of the Schwann cell precursor and immature Schwann cells, followed …
Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after …
IB Wanner, MA Anderson, B Song, J Levine… - Journal of …, 2013 - Soc Neuroscience
Astroglial scars surround damaged tissue after trauma, stroke, infection, or autoimmune
inflammation in the CNS. They are essential for wound repair, but also interfere with axonal …
inflammation in the CNS. They are essential for wound repair, but also interfere with axonal …
[HTML][HTML] EphB signaling directs peripheral nerve regeneration through Sox2-dependent Schwann cell sorting
S Parrinello, I Napoli, S Ribeiro, PW Digby, M Fedorova… - Cell, 2010 - cell.com
The peripheral nervous system has astonishing regenerative capabilities in that cut nerves
are able to reconnect and re-establish their function. Schwann cells are important players in …
are able to reconnect and re-establish their function. Schwann cells are important players in …
The neural crest
R Mayor, E Theveneau - Development, 2013 - journals.biologists.com
The neural crest (NC) is a highly migratory multipotent cell population that forms at the
interface between the neuroepithelium and the prospective epidermis of a developing …
interface between the neuroepithelium and the prospective epidermis of a developing …
Schwann cell precursors; multipotent glial cells in embryonic nerves
KR Jessen, R Mirsky - Frontiers in molecular neuroscience, 2019 - frontiersin.org
The cells of the neural crest, often referred to as neural crest stem cells, give rise to a
number of sub-lineages, one of which is Schwann cells, the glial cells of peripheral nerves …
number of sub-lineages, one of which is Schwann cells, the glial cells of peripheral nerves …
Negative regulation of myelination: relevance for development, injury, and demyelinating disease
KR Jessen, R Mirsky - Glia, 2008 - Wiley Online Library
Dedifferentiation of myelinating Schwann cells is a key feature of nerve injury and
demyelinating neuropathies. We review recent evidence that this dedifferentiation depends …
demyelinating neuropathies. We review recent evidence that this dedifferentiation depends …
Skin-derived precursors generate myelinating Schwann cells that promote remyelination and functional recovery after contusion spinal cord injury
J Biernaskie, JS Sparling, J Liu… - Journal of …, 2007 - Soc Neuroscience
Transplantation of exogenous cells is one approach to spinal cord repair that could
potentially enhance the growth and myelination of endogenous axons. Here, we asked …
potentially enhance the growth and myelination of endogenous axons. Here, we asked …
Development of the Schwann cell lineage: from the neural crest to the myelinated nerve
The myelinating and nonmyelinating Schwann cells in peripheral nerves are derived from
the neural crest, which is a transient and multipotent embryonic structure that also generates …
the neural crest, which is a transient and multipotent embryonic structure that also generates …
Novel signals controlling embryonic Schwann cell development, myelination and dedifferentiation
R Mirsky, A Woodhoo, DB Parkinson… - Journal of the …, 2008 - Wiley Online Library
Immature Schwann cells found in perinatal rodent nerves are generated from Schwann cell
precursors (SCPs) that originate from the neural crest. Immature Schwann cells generate the …
precursors (SCPs) that originate from the neural crest. Immature Schwann cells generate the …