Schwann cells within the peripheral nervous system possess a remarkable regenerative
potential. Current research shows that peripheral nerve‐associated Schwann cells possess …

Schwann cells develop from the neural crest in a well-defined sequence of events. This
involves the formation of the Schwann cell precursor and immature Schwann cells, followed …

Astroglial scars surround damaged tissue after trauma, stroke, infection, or autoimmune
inflammation in the CNS. They are essential for wound repair, but also interfere with axonal …

The peripheral nervous system has astonishing regenerative capabilities in that cut nerves
are able to reconnect and re-establish their function. Schwann cells are important players in …

The neural crest (NC) is a highly migratory multipotent cell population that forms at the
interface between the neuroepithelium and the prospective epidermis of a developing …

The cells of the neural crest, often referred to as neural crest stem cells, give rise to a
number of sub-lineages, one of which is Schwann cells, the glial cells of peripheral nerves …

Dedifferentiation of myelinating Schwann cells is a key feature of nerve injury and
demyelinating neuropathies. We review recent evidence that this dedifferentiation depends …

Transplantation of exogenous cells is one approach to spinal cord repair that could
potentially enhance the growth and myelination of endogenous axons. Here, we asked …

The myelinating and nonmyelinating Schwann cells in peripheral nerves are derived from
the neural crest, which is a transient and multipotent embryonic structure that also generates …

Immature Schwann cells found in perinatal rodent nerves are generated from Schwann cell
precursors (SCPs) that originate from the neural crest. Immature Schwann cells generate the …