A new dawn for managing dyslipidemias: The era of rna-based therapies

C Macchi, CR Sirtori, A Corsini, RD Santos… - Pharmacological …, 2019 - Elsevier
The high occurrence of atherosclerotic cardiovascular disease (ASCVD) events is still a
major public health issue. Although a major determinant of ASCVD event reduction is the …

Bempedoic acid plus ezetimibe fixed-dose combination in patients with hypercholesterolemia and high CVD risk treated with maximally tolerated statin therapy

CM Ballantyne, U Laufs, KK Ray… - European journal of …, 2020 - journals.sagepub.com
Aims The aim of this study was to evaluate the low-density lipoprotein cholesterol lowering
efficacy and safety of a bempedoic acid 180 mg and ezetimibe 10 mg fixed-dose …

Management of dyslipidaemia in patients with coronary heart disease: results from the ESC-EORP EUROASPIRE V survey in 27 countries

G De Backer, P Jankowski, K Kotseva, E Mirrakhimov… - Atherosclerosis, 2019 - Elsevier
Background and aims One of the objectives of the ESC-EORP EUROASPIRE V survey is to
determine how well European guidelines on the management of dyslipidaemias are …

ETC-1002 (Bempedoic acid) for the management of hyperlipidemia: from preclinical studies to phase 3 trials

M Ruscica, M Banach, A Sahebkar… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Tolerability problems in treating hypercholesterolemic patients undergoing
statin treatment are of growing concern to physicians and patients, thus underlining the need …

Combination of bempedoic acid, ezetimibe, and atorvastatin in patients with hypercholesterolemia: a randomized clinical trial

J Rubino, DE MacDougall, LR Sterling, JC Hanselman… - Atherosclerosis, 2021 - Elsevier
Background and aims Many patients with hypercholesterolemia fail to achieve sufficient low-
density lipoprotein cholesterol (LDL-C) lowering despite use of guideline-recommended …

[HTML][HTML] Lipid-lowering therapy use in primary and secondary care in Central and Eastern Europe: DA VINCI observational study

M Vrablik, B Seifert, A Parkhomenko, M Banach… - Atherosclerosis, 2021 - Elsevier
Background and aims Central and Eastern Europe (CEE) is a largely understudied region,
despite having the highest cardiovascular disease mortality in Europe. This analysis aimed …

Low-density lipoprotein cholesterol and adverse cardiovascular events after percutaneous coronary intervention

M Sud, L Han, M Koh, H Abdel-Qadir, PC Austin… - Journal of the American …, 2020 - jacc.org
Background After percutaneous coronary interventions (PCIs), patients remain at high risk of
developing late cardiovascular events. Although controlling low-density lipoprotein …

Attributable burden and expenditure of cardiovascular diseases and associated risk factors in Mexico and other selected mega-countries

K Mendoza-Herrera, A Pedroza-Tobías… - International journal of …, 2019 - mdpi.com
Background: This paper describes the health and economic burden of cardiovascular
diseases (CVD) in Mexico and other mega-countries through a review of literature and …

Screening and Characterization of Some Lactobacillaceae for Detection of Cholesterol-Lowering Activities

M Frappier, J Auclair, S Bouasker… - Probiotics and …, 2022 - Springer
Dyslipidemia, specifically abnormal levels of low-density lipoprotein cholesterol (LDL-C), is
an important risk factor of cardiovascular disease. Evidence showing the promising abilities …

Real-world attainment of low-density lipoprotein cholesterol goals in patients at high risk of cardiovascular disease treated with high-intensity statins: the TERESA …

V Barrios, X Pintó, C Escobar, JF Varona… - Journal of clinical …, 2023 - mdpi.com
Despite steady improvements in cardiovascular disease (CVD) prevention, a scarce
proportion of patients achieve the recommended LDL-C goals, even under high-intensity …