Preclinical animal anxiety research–flaws and prejudices
A Ennaceur, PL Chazot - Pharmacology research & …, 2016 - Wiley Online Library
The current tests of anxiety in mice and rats used in preclinical research include the elevated
plus‐maze (EPM) or zero‐maze (EZM), the light/dark box (LDB), and the open‐field (OF) …
plus‐maze (EPM) or zero‐maze (EZM), the light/dark box (LDB), and the open‐field (OF) …
Investigating the effect of physiological need states on palatability and motivation using microstructural analysis of licking
The study of consummatory responses during food intake represents a unique opportunity to
investigate the physiological, psychological and neurobiological processes that control …
investigate the physiological, psychological and neurobiological processes that control …
Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades
D Wahlsten, A Bachmanov, DA Finn… - Proceedings of the …, 2006 - National Acad Sciences
If we conduct the same experiment in two laboratories or repeat a classical study many
years later, will we obtain the same results? Recent research with mice in neural and …
years later, will we obtain the same results? Recent research with mice in neural and …
Breadth of tuning in taste afferent neurons varies with stimulus strength
Gustatory stimuli are detected by taste buds and transmitted to the hindbrain via sensory
afferent neurons. Whether each taste quality (sweet, bitter and so on) is encoded by …
afferent neurons. Whether each taste quality (sweet, bitter and so on) is encoded by …
Neural landscape is associated with functional outcomes in irradiated patients with oropharyngeal squamous cell carcinoma
S Islam, FO Gleber-Netto, CF Mulcahy… - Science translational …, 2024 - science.org
The incidence of human papilloma virus–mediated oropharyngeal squamous cell carcinoma
(OPSCC) has increased over the past 40 years, particularly among young individuals with a …
(OPSCC) has increased over the past 40 years, particularly among young individuals with a …
[HTML][HTML] Modulation of taste responsiveness by the satiation hormone peptide YY
MS La Sala, MD Hurtado, AR Brown… - The FASEB …, 2013 - ncbi.nlm.nih.gov
It has been hypothesized that the peripheral taste system may be modulated in the context of
an animal's metabolic state. One purported mechanism for this phenomenon is that …
an animal's metabolic state. One purported mechanism for this phenomenon is that …
Orosensory detection of sucrose, maltose, and glucose is severely impaired in mice lacking T1R2 or T1R3, but Polycose sensitivity remains relatively normal
Y Treesukosol, AC Spector - American Journal of …, 2012 - journals.physiology.org
Evidence in the literature supports the hypothesis that the T1R2+ 3 heterodimer binds to
compounds that humans describe as sweet. Here, we assessed the necessity of the T1R2 …
compounds that humans describe as sweet. Here, we assessed the necessity of the T1R2 …
An analysis of licking microstructure in three strains of mice
AW Johnson, A Sherwood, DR Smith, M Wosiski-Kuhn… - Appetite, 2010 - Elsevier
Mouse models of feeding provide a useful tool for elucidating the molecular pathways of
energy regulation. The majority of studies in mice have been limited to intake analyses …
energy regulation. The majority of studies in mice have been limited to intake analyses …
C57BL/6J and DBA/2J mice vary in lick rate and ingestive microstructure
JD Boughter Jr, JP Baird, J Bryant… - Genes, Brain and …, 2007 - Wiley Online Library
Fluid licking in mice is an example of a rhythmic behavior thought to be under the control of
a central pattern generator. Inbred strains of mice have been shown to differ in mean or …
a central pattern generator. Inbred strains of mice have been shown to differ in mean or …
Ethanol drinking microstructure of a high drinking in the dark selected mouse line
AM Barkley‐Levenson… - Alcoholism: Clinical and …, 2012 - Wiley Online Library
Background The High Drinking in the Dark (HDID) selected mouse line was bred for high
blood ethanol (E t OH) concentration (BEC) following the limited access drinking in the dark …
blood ethanol (E t OH) concentration (BEC) following the limited access drinking in the dark …