Strategies toward rheumatoid arthritis therapy; the old and the new
Currently, medications used to treat rheumatoid arthritis (RA) are glucocorticoids (GCs) and
nonsteroidal anti‐inflammatory drugs (NSAIDs), predominantly used for controlling the pain …
nonsteroidal anti‐inflammatory drugs (NSAIDs), predominantly used for controlling the pain …
Genetic implications in the pathogenesis of rheumatoid arthritis; an updated review
Three important factors, including genetics, environment factors and autoimmunity play a
role in the pathogenesis of rheumatoid arthritis (RA). The heritability of RA has been …
role in the pathogenesis of rheumatoid arthritis (RA). The heritability of RA has been …
Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis
K Furuta, Q Guo, KD Pavelko, JH Lee… - The Journal of …, 2021 - Am Soc Clin Investig
Monocyte homing to the liver and adhesion to the liver sinusoidal endothelial cells (LSECs)
are key elements in nonalcoholic steatohepatitis (NASH) pathogenesis. We reported …
are key elements in nonalcoholic steatohepatitis (NASH) pathogenesis. We reported …
Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions
LD Ferguson, S Siebert, IB McInnes… - Nature Reviews …, 2019 - nature.com
Cardiometabolic comorbidities present a considerable burden for patients with rheumatoid
arthritis (RA) or psoriatic arthritis (PsA). Both RA and PsA are associated with an increased …
arthritis (RA) or psoriatic arthritis (PsA). Both RA and PsA are associated with an increased …
Extra-articular rheumatoid arthritis
E Marcucci, E Bartoloni, A Alunno, MC Leone, G Cafaro… - 2018 - reumatismo.org
Rheumatoid arthritis (RA) is a chronic inflammatory disease that mainly affects the joints,
though a consistent proportion of patients may also display extra articular manifestations …
though a consistent proportion of patients may also display extra articular manifestations …
Consensus recommendations on managing the selected comorbidities including cardiovascular disease, osteoporosis, and interstitial lung disease in rheumatoid …
KH Yu, HH Chen, TT Cheng, YJ Jan, MY Weng, YJ Lin… - Medicine, 2022 - journals.lww.com
Background: Rheumatoid arthritis (RA)-related comorbidities, including cardiovascular
disease (CVD), osteoporosis (OP), and interstitial lung disease (ILD), are sub-optimally …
disease (CVD), osteoporosis (OP), and interstitial lung disease (ILD), are sub-optimally …
Autoimmune rheumatic diseases and vascular function: the concept of autoimmune atherosclerosis
AM Hedar, MH Stradner, A Roessler… - Journal of clinical …, 2021 - mdpi.com
Autoimmune rheumatic diseases (AIRDs) with unknown etiology are increasing in incidence
and prevalence. Up to 5% of the population is affected. AIRDs include rheumatoid arthritis …
and prevalence. Up to 5% of the population is affected. AIRDs include rheumatoid arthritis …
Lower serum levels of Meteorin-like/Subfatin in patients with coronary artery disease and type 2 diabetes mellitus are negatively associated with insulin resistance and …
M Dadmanesh, H Aghajani, R Fadaei, K Ghorban - PloS one, 2018 - journals.plos.org
Meteorin-like (Metrnl) is a newly discovered adipokine with favorable effect on insulin
sensitivity. Previous studies have reported lower levels of Metrnl in obese patients. However …
sensitivity. Previous studies have reported lower levels of Metrnl in obese patients. However …
Exploring the therapeutic promise of targeting HMGB1 in rheumatoid arthritis
High mobility group box-1 (HMGB1) protein is a diverse, single polypeptide moiety, present
in mammalian eukaryotic cells. In response to stimuli, this nuclear protein is actively …
in mammalian eukaryotic cells. In response to stimuli, this nuclear protein is actively …
Decreased serum levels of CTRP12/adipolin in patients with coronary artery disease in relation to inflammatory cytokines and insulin resistance
Coronary artery disease (CAD) is the leading cause of death worldwide. Atherosclerosis as
the main underlying mechanism of CAD is associated with inflammation and adipose tissue …
the main underlying mechanism of CAD is associated with inflammation and adipose tissue …