Human serum albumin from recombinant DNA technology: challenges and strategies

Z Chen, Y He, B Shi, D Yang - … et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
Background As the most abundant protein in the blood, human serum albumin (HSA) plays
an important role in maintaining plasma oncotic pressure and fluid balance between the …

Electrochemical detection of bacterial endotoxin lipopolysaccharide (LPS) on gold electrode modified with DAL-PEG-DK5-PEG-OH-Antimicrobial peptide conjugate

P Kosikowska-Adamus, A Golda, J Ryl… - Talanta, 2024 - Elsevier
This work describes fabrication of gold electrodes modified with peptide conjugate DAL-PEG-
DK5-PEG-OH that enables ultra-sensitive detection of lipopolysaccharide (LPS) isolated …

Analysis of secretome and N-glycosylation of Chlorella species

J Choi, JH Shin, HJ An, MJ Oh, SR Kim - Algal Research, 2021 - Elsevier
Chlorella, unicellular green algae, has been spotlighted not only as a model organism but
also as a cell factory for various metabolites, biofuels and biopharmaceuticals. In order to …

Allantoin as a solid phase adsorbent for removing endotoxins

V Vagenende, TJ Ching, RJ Chua, P Gagnon - Journal of Chromatography …, 2013 - Elsevier
In this study we present a simple and robust method for removing endotoxins from protein
solutions by using crystals of the small-molecule compound 2, 5-dioxo-4-imidazolidinyl urea …

Integrated strategy for the separation of endotoxins from biofluids. LPS capture on newly synthesized protein

A Basauri, M Fallanza, L Giner-Robles… - Separation and …, 2021 - Elsevier
Abstract Endotoxin, or lipopolysaccharide (LPS), is recognized as the most powerful
microbial mediator implicated in the pathogenesis of sepsis, a life-threatening organ …

Preparation and characterization of polymyxin B-and histidine-coupled magnetic nanoparticles for purification of biologics from acquired endotoxin contamination

ASM Salah, LA Hassan, F Fathallaa… - Beni-Suef University …, 2022 - Springer
Background Endotoxin is a major process-related impurity that can act as a strong
immunostimulant leading to fever and hypotensive shock. Thus, the US FDA and …

Microbial quality concerns for biopharmaceuticals

F Lotfipour, S Hallaj-Nezhadi - Latest Research into Quality …, 2012 - books.google.com
Finding an appropriate definition or a clear classification for biologically occurring pharma‐-
ceutical products is a complicated task because of overlapping borders and consequent mis …

Part I: Surface modification of magnetic nanoparticles for the recovery of plasmid DNA and exclusion of endotoxins in recombinant DNA assays; Part II: Biosafety and …

MAL Young - 2016 - repository.arizona.edu
Part II: Biosafety and Environmental Health Program Implementation Related to
Manufacturing and Research of Medical Diagnostic Systems Focusing on Biopsy-Based …

[PDF][PDF] Screening Microbial Contamination and Physical properties of Some Drugs in Erbil-Kurdistan Region-Iraq

PA Hamasaeed, KKSHM Alsakee - Journal of University of Babylon, 2017 - iasj.net
Present study attempted to determine the microbiological quality and the physical properties
of same drug commonly used for disease medication in Erbil. A total of 3924 drugs samples …

[引用][C] 超滤技术在蛋白质分离纯化中的应用

王健, 叶波平 - 药学进展, 2012