The literature was reviewed to summarize the current understanding of the role of ciliated
ependymal cells in the mammalian brain. Previous reviews were summarized. Publications …

The neuroepithelium is a germinal epithelium containing progenitor cells that produce
almost all of the central nervous system cells, including the ependyma. The neuroepithelium …

Adult neurogenesis has been convincingly demonstrated in two regions of the mammalian
brain: the sub-granular zone (SGZ) of the dentate gyrus (DG) in the hippocampus, and the …

The pathophysiology of congenital and neonatal hydrocephalus is not well understood
although the prognosis for patients with this disorder is far from optimal. A major obstacle to …

Fetal hydrocephalus (FH), characterized by the accumulation of cerebrospinal fluid, an
enlarged head, and neurological dysfunction, is one of the most common neurological …

Periventricular heterotopia (PH) is a disorder characterized by neuronal nodules, ectopically
positioned along the lateral ventricles of the cerebral cortex. Mutations in either of two …

To determine if ventricular zone (VZ) and subventricular zone (SVZ) alterations are
associated with intraventricular hemorrhage (IVH) and posthemorrhagic hydrocephalus, we …

Apical radial glia comprise the pseudostratified neuroepithelium lining the embryonic lateral
ventricles and give rise to the extensive repertoire of pyramidal neuronal subtypes of the …

Hydrocephalic hyh mutant mice undergo a programmed loss of the neuroepithelium/
ependyma followed by a reaction of periventricular astrocytes, which form a new cell layer …

Fetal-onset hydrocephalus affects 1 to 3 per 1,000 live births. It is not only a disorder of
cerebrospinal fluid dynamics but also a brain disorder that corrective surgery does not …