Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by
prolonged hyperglycemia that leads to long-term health consequences. It is estimated that …

The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

The ability to form biofilms is a crucial virulence trait for several microorganisms, including
Klebsiella pneumoniae–a Gram-negative encapsulated bacterium often associated with …

The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are
still poorly understood, and current therapies are limited. Poor wound healing after trauma …

Impaired wound healing in chronic wounds has been a significant challenge for clinicians
and researchers for decades. Traditional herbal medicine (THM) has a long history of …

The chronic nature and associated complications of nonhealing wounds have led to the
emergence of nanotechnology-based therapies that aim at facilitating the healing process …

Bacterial resistance to antibiotics have become one of the most severe threats in global
public health, so the development of new-style antimicrobial agents is urgent. In this work …

The skin microbiota is intimately coupled with cutaneous health and disease. Interactions
between commensal microbiota and the multiple cell types involved in cutaneous wound …

Significance: Keratinocytes, a major cellular component of the epidermis, are responsible for
restoring the epidermis after injury through a process termed epithelialization. This review …

Chronic leg ulcers affect 1–2% of the general population and are related to increased
morbidity and health costs. Staphylococcus aureus and Pseudomonas aeruginosa are the …