Doxorubicin-loaded micelles in tumor cell-specific chemotherapy

YQ Almajidi, MM Kadhim, F Alsaikhan, AT Jalil… - Environmental …, 2023 - Elsevier
Nanomedicine is a field that combines biology and engineering to improve disease
treatment, particularly in cancer therapy. One of the promising techniques utilized in this …

MicroRNAs: important players in breast cancer angiogenesis and therapeutic targets

BM Hussen, ST Abdullah, MF Rasul, A Salihi… - Frontiers in molecular …, 2021 - frontiersin.org
The high incidence of breast cancer (BC) is linked to metastasis, facilitated by tumor
angiogenesis. MicroRNAs (miRNAs or miRs) are small non-coding RNA molecules that …

Functional interplay between long non-coding RNAs and Breast CSCs

BM Hussen, RK Kheder, ST Abdullah, HJ Hidayat… - Cancer Cell …, 2022 - Springer
Breast cancer (BC) represents aggressive cancer affecting most women's lives globally.
Metastasis and recurrence are the two most common factors in a breast cancer patient's …

Signaling pathways modulated by miRNAs in breast cancer angiogenesis and new therapeutics

BM Hussen, A Salihi, ST Abdullah, MF Rasul… - … -Research and Practice, 2022 - Elsevier
MicroRNAs (miRNAs) act as oncogenes or tumor suppressors by suppressing the
expression of target genes, some of which are engaged in angiogenic signaling pathways …

Understanding cancer's defense against topoisomerase-active drugs: A comprehensive review

NK Sharma, A Bahot, G Sekar, M Bansode, K Khunteta… - Cancers, 2024 - mdpi.com
Simple Summary Increasing number of cancer patients and significant mortality among
these patients are attributed to many factors including anticancer drug resistance. Among a …

Investigations on anticancer activity of Eu3+ doped hydroxyapatite nanocomposites against MCF7 and 4T1 breast cancer cell lines: A structural and luminescence …

KS Manogna, BDP Raju, GR Reddy, P Kallem… - Heliyon, 2024 - cell.com
Breast cancer remains a significant global health concern, necessitating the development of
novel therapeutic approaches. In this study, we investigate the role of Eu 3+ doped …

The role of circRNAs in resistance to doxorubicin

M Sanati, S Ghafouri-Fard - Cell Communication and Signaling, 2024 - Springer
Doxorubicin is an anthracyline recognized as an antitumor antibiotic agent. It is widely used
in the chemotherapeutic regimens in different types of cancers. Resistance to doxorubicin is …

A review on the role of miR-671 in human disorders

S Ghafouri-Fard, A Askari, BM Hussen… - Frontiers in Molecular …, 2022 - frontiersin.org
miR-671 is encoded by a gene on 7q36. 1 and contributes to the pathogenesis of a variety of
disorders, including diverse types of cancers, atherosclerosis, ischemic stroke, liver fibrosis …

Curcumin attenuates doxorubicin-induced cardiotoxicity via suppressing oxidative Stress, preventing inflammation and apoptosis: Ultrastructural and computational …

AA Shati, RA Eid, AF El-Kott, YA Alqahtani, AS Shatoor… - Heliyon, 2024 - cell.com
Currently, doxorubicin (DOX) is one of the medications commonly used in chemotherapy to
treat different types of tumors. Nonetheless, despite being effective in multiple tumors, yet its …

Substance P prevents doxorubicin‑induced cardiomyocyte injury by regulating apoptosis and autophagy: In vitro and in vivo evidence

FX Chen, Q Wan, QL Li, J Fang… - Molecular medicine …, 2022 - spandidos-publications.com
The function of substance P (SP) in myocardial ischemia is well understood, but its effects on
congestive heart failure are unclear. The present study aimed to use in vitro and in vivo …