New insights in topical drug delivery for skin disorders: from a nanotechnological perspective

N Raina, R Rani, VK Thakur, M Gupta - ACS omega, 2023 - ACS Publications
Skin, the largest organ in humans, is an efficient route for the delivery of drugs as it
circumvents several disadvantages of the oral and parenteral routes. These advantages of …

Advances and future perspectives in epithelial drug delivery

Y Mohammed, A Holmes, PCL Kwok, T Kumeria… - Advanced Drug Delivery …, 2022 - Elsevier
Epithelial surfaces protect exposed tissues in the body against intrusion of foreign materials,
including xenobiotics, pollen and microbiota. The relative permeability of the various …

Overlay databank unlocks data-driven analyses of biomolecules for all

AM Kiirikki, HS Antila, LS Bort, P Buslaev… - Nature …, 2024 - nature.com
Tools based on artificial intelligence (AI) are currently revolutionising many fields, yet their
applications are often limited by the lack of suitable training data in programmatically …

Porcupine-inspired microneedles coupled with an adhesive back patching as dressing for accelerating diabetic wound healing

T Liu, Y Sun, G Jiang, W Zhang, R Wang, L Nie… - Acta Biomaterialia, 2023 - Elsevier
Diabetes chronic wound is a severe and frequently occurring medical issue in patients with
diabetes that often leads to more serious complications. Microneedles (MNs) can be used …

Formulation and development of novel lipid-based combinatorial advanced nanoformulation for effective treatment of non-melanoma skin cancer

N Hasan, M Imran, M Nadeem, D Jain, K Haider… - International journal of …, 2023 - Elsevier
Non-melanoma skin cancer is one of the most common malignancies reported with high
number of morbidities, demanding an advanced treatment option with superior …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Microneedle‐assisted transdermal delivery of nanoparticles: Recent insights and prospects

AJ Guillot, M Martínez‐Navarrete… - Wiley …, 2023 - Wiley Online Library
Transdermal delivery of drugs offers an interesting alternative for the administration of
molecules that present certain troubles when delivered by the oral route. It can produce …

[HTML][HTML] Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders

Y Gu, Q Bian, Y Zhou, Q Huang, J Gao - Asian Journal of Pharmaceutical …, 2022 - Elsevier
The hair follicle is not only a critical penetration route in percutaneous absorption but also
has been recognized to be a target for hair follicle-associated disorders, such as …

Exploring the remarkable chemotherapeutic potential of polyphenolic antioxidants in battling various forms of cancer

M Imran, A Insaf, N Hasan, VV Sugandhi, D Shrestha… - Molecules, 2023 - mdpi.com
Plant-derived compounds, specifically antioxidants, have played an important role in
scavenging the free radicals present under diseased conditions. The persistent generation …

Effect of penetration enhancers on transdermal delivery of oxcarbazepine, an antiepileptic drug using microemulsions

A Virani, V Puri, H Mohd, B Michniak-Kohn - Pharmaceutics, 2023 - mdpi.com
Oxcarbazepine (OXC) is an anticonvulsant drug, indicated for the treatment of the
neurological disorder, epilepsy. The objective of the present study was to evaluate the …