CircRNAs: role in human diseases and potential use as biomarkers

L Verduci, E Tarcitano, S Strano, Y Yarden… - Cell death & …, 2021 - nature.com
Circular RNAs (circRNAs) are a class of endogenous RNAs characterized by a covalent
loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively …

[HTML][HTML] Review on circular RNAs and new insights into their roles in cancer

X Tang, H Ren, M Guo, J Qian, Y Yang, C Gu - … and structural biotechnology …, 2021 - Elsevier
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …

The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer

J Xu, J Xu, X Liu, J Jiang - Cell death discovery, 2022 - nature.com
Abstract Non-coding RNAs (ncRNAs), which occupy the vast majority of human transcripts
are known for their inability to encode proteins. NcRNAs consist of a diverse range of RNA …

Competing endogenous RNA (ceRNA) cross talk and language in ceRNA regulatory networks: a new look at hallmarks of breast cancer

R Abdollahzadeh, A Daraei, Y Mansoori… - Journal of cellular …, 2019 - Wiley Online Library
Breast cancer (BC) is the most frequently occurring malignancy in women worldwide.
Despite the substantial advancement in understanding the molecular mechanisms and …

circTADA2As suppress breast cancer progression and metastasis via targeting miR-203a-3p/SOCS3 axis

JZ Xu, CC Shao, XJ Wang, X Zhao, JQ Chen… - Cell death & …, 2019 - nature.com
More and more evidence indicates that circular RNAs (circRNAs) have important roles in
several diseases, especially in cancers. However, their involvement remains to be …

Function and clinical significance of circRNAs in solid tumors

Y Geng, J Jiang, C Wu - Journal of hematology & oncology, 2018 - Springer
Circular RNA (circRNA) is a new type of endogenous non-coding RNAs (ncRNAs). circRNA
regulates gene expression in many biological processes, and it also participates in the …

[HTML][HTML] circEPSTI1 as a prognostic marker and mediator of triple-negative breast cancer progression

BO Chen, W Wei, X Huang, X Xie, Y Kong, D Dai… - Theranostics, 2018 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) represent a class of non-coding RNAs that play a vital role in
modulating gene expression and several pathological responses. However, the expression …

Characterization of hsa_circ_0004277 as a new biomarker for acute myeloid leukemia via circular RNA profile and bioinformatics analysis

W Li, C Zhong, J Jiao, P Li, B Cui, C Ji… - International journal of …, 2017 - mdpi.com
Circular RNAs (circRNAs) represent a widespread class of non-coding RNAs, which drew
little attention in the past. Recently, limited data showed their promising future to act as …

[HTML][HTML] Identification of circular RNAs as a promising new class of diagnostic biomarkers for human breast cancer

L Lü, J Sun, P Shi, W Kong, K Xu, B He, S Zhang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Endogenous noncoding circular RNAs (circRNAs) have gained attention for their
involvement in carcinogenesis, but their expression pattern in breast cancer has remained …

Circular RNAs as potential biomarkers in breast cancer

FDE De Palma, F Salvatore, JG Pol, G Kroemer… - Biomedicines, 2022 - mdpi.com
Due to the high heterogeneity and initially asymptomatic nature of breast cancer (BC), the
management of this disease depends on imaging together with immunohistochemical and …