Salient achievements in synthetic organic chemistry enabled by mechanochemical activation

E Juaristi, CG Avila-Ortiz - Synthesis, 2023 - thieme-connect.com
Although known for millennia, it is only recently that mechanochemistry has received serious
attention by chemists. Indeed, during the past 15 years an extraordinary number of reports …

Spiers Memorial Lecture: Mechanochemistry, tribochemistry, mechanical alloying–retrospect, achievements and challenges

E Boldyreva - Faraday discussions, 2023 - pubs.rsc.org
Spiers Memorial Lecture: Mechanochemistry, tribochemistry, mechanical alloying –
retrospect, achievements and challenges - Faraday Discussions (RSC Publishing) DOI:10.1039/D2FD00149G …

Mechanochemical Assisted Chemoselective and Stereoselective Hydrogen‐Bonding Catalyzed Addition of Dithiomalonates to Enones

ŻA Mała, MJ Janicki, RW Góra… - Advanced Synthesis …, 2023 - Wiley Online Library
Dithiomalonates proved to be active nucleophiles in the stereoselective additions to
chalcones, dienones, and en‐ynones affording the desired Michael adducts with moderate …

Asymmetric Organocatalysis Under Mechanochemical Conditions

V Némethová, D Krištofíková, M Mečiarová… - The Chemical …, 2023 - Wiley Online Library
Asymmetric organocatalysis is a robust methodology providing access to numerous
valuable compounds while having green chemistry principles in mind. The realization of …

Synthesis of Quinazolinones and Benzothiazoles Using α-Keto Acids under Ball Milling

A Sharma, J Singh, A Sharma - The Journal of Organic Chemistry, 2024 - ACS Publications
Mechanochemistry refers to the initiation of chemical reactions via mechanical forces such
as milling, grinding, or shearing to achieve the chemical transformations. As a manifestation …

Catalytically generated noncovalent ammonium dienolate: a versatile platform for the development of organocatalytic asymmetric cascade reactions

JB Lin, DS Ji, PF Xu - Science China Chemistry, 2024 - Springer
Organocatalytic cascade reactions represent a powerful strategy for the rapid construction of
complex chiral molecules with multiple stereocenters from simple substrates under mild …

DABCO-catalyzed mono-and bisallylation of β, γ-unsaturated ketones with Morita–Baylis–Hillman carbonates

G Yue, B Du, Q Wang, S Cheng, L Ma, C Lu… - New Journal of …, 2024 - pubs.rsc.org
Allylation of β, γ-unsaturated ketones with Morita–Baylis–Hillman carbonates in the
presence of 5 mol% DABCO in dioxane at room temperature gave 2-alkoxycarbonylallyl β, γ …

3 Ball-milling (mechanochemical) synthesis of bioactive heterocycles

D Margetić - Solvent-Free Synthesis: Bioactive Heterocycles, 2023 - degruyter.com
The first accounts on the solid-state synthesis of biologically or pharmaceutically active
heterocycles came from manual mortar and pestle reactions, which were recently reviewed …

Fluorinated Chiral Pyrans Obtained via Mechanochemical Organocatalytic Michael/oxa‐Michael Cascade

K Stankovianska, V Némethová… - European Journal of …, 2024 - Wiley Online Library
Fluorine‐containing compounds are important in medicine or crop‐protection. Herein, we
show asymmetric organocatalytic Michael/oxa‐Michael cascade leading to chiral fluorinated …

Synthesis and Crystal Structure Analysis of NH4[Zn(cma)(H2O)2]·H2O Using IAM and HAR Approaches

J Chrappová, YR Pateda, E Rakovský - Journal of Chemical …, 2023 - Springer
The crystal structure of NH4 [Zn (cma)(H2O) 2]· H2O (cma 3–= N-carboxymethylaspartate (3–
)) is determined by single crystal X-ray structure analysis. The orthorombic crystals (P …