[HTML][HTML] Solid lipid nanoparticles, an effective carrier for classical antifungal drugs

S Almawash - Saudi Pharmaceutical Journal, 2023 - Elsevier
Solid-lipid nanoparticles (SLNs) are an innovative group of nanosystems used to deliver
medicine to their respective targets with better efficiency and bioavailability in contrast to …

Superficial Dermatophytosis across the World's Populations: Potential Benefits from Nanocarrier-Based Therapies and Rising Challenges

P Keshwania, N Kaur, J Chauhan, G Sharma… - ACS …, 2023 - ACS Publications
The most prevalent infection in the world is dermatophytosis, which is a major issue with
high recurrence and can affect the entire body including the skin, hair, and nails. The major …

Lipid based nanocarriers: A novel paradigm for topical antifungal therapy

S Nene, S Shah, N Rangaraj, NK Mehra… - Journal of Drug Delivery …, 2021 - Elsevier
Superficial fungal infections manifesting the skin have become prevalent today. Even though
there has been a substantial number of antifungal drugs approved for treating topical fungal …

Potent antifungal agents and use of nanocarriers to improve delivery to the infected site: A systematic review

S Nagaraj, S Manivannan… - Journal of Basic …, 2021 - Wiley Online Library
There are four major classes of antifungals with the predominant mechanism of action being
targeting of cell wall or cell membrane. As in other drugs, low solubility of these compounds …

Development of a luliconazole nanoemulsion as a prospective ophthalmic delivery system for the treatment of fungal keratitis: in vitro and in vivo evaluation

J Yang, Z Liang, P Lu, F Song, Z Zhang, T Zhou, J Li… - Pharmaceutics, 2022 - mdpi.com
Luliconazole (LCZ), a novel imidazole drug, has broad-spectrum and potential antifungal
effects, which makes it a possible cure for fungal keratitis; nevertheless, its medical use in …

Formulation and optimization of butenafine-loaded topical nano lipid carrier-based gel: characterization, irritation study, and anti-fungal activity

WA Mahdi, SI Bukhari, SS Imam, S Alshehri, A Zafar… - Pharmaceutics, 2021 - mdpi.com
The present study aims to prepare and optimize butenafine hydrochloride NLCs formulation
using solid and liquid lipid. The optimized selected BF-NLCopt was further converted into …

Bacteriophage entrapped chitosan microgel for the treatment of biofilm-mediated polybacterial infection in burn wounds

D Dehari, DN Kumar, A Chaudhuri, A Kumar… - International Journal of …, 2023 - Elsevier
Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) bacteria
are most commonly present in burn wound infections. Multidrug resistance (MDR) and …

Luliconazole Nail Lacquer for the Treatment of Onychomycosis: Formulation, Characterization and In Vitro and Ex Vivo Evaluation

D Dehari, AK Mehata, V Priya, D Parbat, D Kumar… - AAPS …, 2022 - Springer
Onychomycosis is the most common fungal infection of the nail affecting the skin under the
fingertips and the toes. Currently, available therapy for onychomycosis includes oral and …

Eumycetoma causative agents are inhibited in vitro by luliconazole, lanoconazole and ravuconazole

B Nyuykonge, W Lim, L van Amelsvoort, A Bonifaz… - Mycoses, 2022 - Wiley Online Library
Introduction Eumycetoma is a subcutaneous mutilating disease that can be caused by many
different fungi. Current treatment consists of prolonged itraconazole administration in …

Fabrication of gelatin coated polycaprolactone nanofiber scaffolds co-loaded with luliconazole and naringenin for treatment of Candida infected diabetic wounds

M Manjit, K Kumar, M Kumar, A Jha, K Bharti… - International Journal of …, 2024 - Elsevier
The current study focuses on the development of gelatin-coated polycaprolactone (PCL)
nanofibers co-loaded with luliconazole and naringenin for accelerated healing of infected …