Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

The intricate nature of Alzheimer's disease (AD) pathogenesis poses a persistent obstacle to
drug development. In recent times, neuroinflammation has emerged as a crucial pathogenic …

Drug development for Alzheimer's disease, the leading cause of dementia, has been a long-
standing challenge. Saponins, which are steroid or triterpenoid glycosides with various …

Alzheimer's disease is characterized by progressive cognitive decline, and behavioural and
psychological symptoms of dementia are common. The APOE ε4 allele, a genetic risk factor …

Over the last decade, peroxisome proliferator-activated receptor (PPAR-γ) has emerged as
one of the important therapeutic targets in several metabolic and neurodegenerative …

Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a
common side effect of paclitaxel, affecting 30‐50% of patients. Increased survival and …

Traumatic brain injury (TBI) is a disabling neurotraumatic condition and the leading cause of
injury-related deaths and disability in the United States. Attenuation of neuroinflammation …

Parkinson's Disease (PD) is the most common movement disorder, and the strongest
genetic risk factor for PD is mutations in the glucocerebrosidase gene (GBA). Mutations in …

Alzheimer's disease (AD) is a neurological disorder. It is caused by accumulation of amyloid
beta (Aβ) plaques and tau tangles, which gradually leads to cognitive decline and memory …

Background and Aim Previous studies of our research group have shown that Chuanxiong
Renshen Decoction (CRD) has the effect of treating AD, but the exact mechanism of its effect …