The growing field of tumor metabolism has greatly expanded our knowledge of metabolic
reprogramming in cancer. Apart from their established roles, various metabolic enzymes and …

Cardiovascular disease (CVD), including heart attack, stroke, heart failure, arrhythmia, and
other congenital heart diseases remain the leading cause of morbidity and mortality …

The composition of the intestinal microbiome varies considerably between individuals and is
correlated with health. Understanding the extent to which, and how, host genetics …

In situ tumor vaccination is preliminarily pursued to strengthen antitumor immune response.
Immunogenic tumor cell death spontaneously releases abundant antigens and adjuvants for …

Circulating tumor cells (CTCs) are recognized as direct seeds of metastasis. However, CTC
count may not be the “best” indicator of metastatic risk because their heterogeneity is …

Oxidative stress modulates carcinogenesis in the liver; however, direct evidence for
metabolic control of oxidative stress during pathogenesis, particularly, of progression from …

Metabolic reprogramming is known as an emerging mechanism of chemotherapy
resistance, but the metabolic signatures of pancreatic ductal adenocarcinomas (PDACs) …

Cepharanthine (CEP), a natural compound extracted from Stephania cepharantha Hayata,
has been found to have the potential to treat a variety of tumors in recent years. This study …

Transaldolase deficiency predisposes to chronic liver disease progressing from cirrhosis to
hepatocellular carcinoma (HCC). Transition from cirrhosis to hepatocarcinogenesis depends …

The well-documented anticarcinogenic properties of natural polyphenolic proanthocyanidins
(OPC) have been primarily attributed to their antioxidant and anti-inflammatory potency …