Natural resources continue to be an invaluable source of new, novel chemical entities of
therapeutic utility due to the vast structural diversity observed in them. The quest for new and …

Objectives The main objective of present review is to explore and evaluate the effectiveness
of recently developed methods to improve the bioavailability of orally administered …

This work aimed to optimize a celecoxib (CXB)-loaded solid lipid nanoparticles (SLN) colon
delivery system for the enhancement of anticancer activity. An ultrasonic melt-emulsification …

The development of nano-dosage forms of phytochemicals represents a significant progress
of the scientific approach in the biomedical research. The aim of this study was to assess the …

Valsartan (Val) is an important antihypertensive medication with poor absorption and low
oral bioavailability. These constraints are due to its poor solubility and dissolution rate. The …

Review Page 1 Copyright © 2014 American Scientific Publishers All rights reserved Printed in
the United States of America Review Journal of Biomedical Nanotechnology Vol. 10, 2107–2148 …

Nanotechnology-based bitherapy has recently emerged as an effective strategy to overcome
biomedical barriers against successful anticancer therapy. The study aimed to evaluate lipid …

The topically applied drugs as drops are washed off from the eye in very short period,
resulting in low ocular bioavailability of drugs. Number of approaches have been attempted …

In the current study, 5-FU-loaded nanoparticles (NPs) were prepared using polylactic-co-
glycolic acid (PLGA), polycaprolactone (PCL), di-block poly lactide-co-caprolactone (PLCL) …

A wide range of FDA (Food and Drug Administration, US) approved synthetic and natural
polymers have already entered in medical and pharmaceutical markets (Mansour et al …