Accelerating research on biological aging and mental health: Current challenges and future directions

LKM Han, JE Verhoeven, AR Tyrka… - …, 2019 - Elsevier
Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

DJ Harvey - Mass spectrometry reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

[HTML][HTML] Genetic regulation of post-translational modification of two distinct proteins

A Landini, I Trbojević-Akmačić, P Navarro… - Nature …, 2022 - nature.com
Post-translational modifications diversify protein functions and dynamically coordinate their
signalling networks, influencing most aspects of cell physiology. Nevertheless, their genetic …

Revealing the biological attributes of N-glycan isomers in breast cancer brain metastasis using porous graphitic carbon (PGC) liquid chromatography-tandem mass …

W Peng, M Goli, P Mirzaei… - Journal of proteome …, 2019 - ACS Publications
Breast cancer is a leading cancer in women and is considered to be the second-most
common metastatic cancer following lung cancer. An estimated 10–16% of breast cancer …

Defining the genetic control of human blood plasma N-glycome using genome-wide association study

SZ Sharapov, YA Tsepilov, L Klaric… - Human molecular …, 2019 - academic.oup.com
Glycosylation is a common post-translational modification of proteins. Glycosylation is
associated with a number of human diseases. Defining genetic factors altering glycosylation …

[HTML][HTML] Integrated transcriptomics, proteomics, and glycomics reveals the association between up-regulation of sialylated N-glycans/integrin and breast cancer brain …

W Peng, R Zhu, S Zhou, P Mirzaei, Y Mechref - Scientific reports, 2019 - nature.com
Breast cancer brain metastasis has been recognized as one of the central issues in breast
cancer research. The elucidation of the processes and pathways that mediate this step will …

[HTML][HTML] Sample preparation scale-up for deep N-glycomic analysis of human serum by capillary electrophoresis and CE-ESI-MS

M Szigeti, A Guttman - Molecular & Cellular Proteomics, 2019 - ASBMB
We introduce an efficient sample preparation workflow to facilitate deep N-glycomics
analysis of the human serum by capillary electrophoresis with laser induced fluorescence …

[HTML][HTML] Serum N-glycan profiles differ for various breast cancer subtypes

GCM Vreeker, KMH Vangangelt, MR Bladergroen… - Glycoconjugate …, 2021 - Springer
Breast cancer is the most prevalent cancer in women. Early detection of this disease
improves survival and therefore population screenings, based on mammography, are …

Quantitative clinical glycomics strategies: a guide for selecting the best analysis approach

MW Patabandige, LD Pfeifer… - Mass spectrometry …, 2022 - Wiley Online Library
Glycans introduce complexity to the proteins to which they are attached. These modifications
vary during the progression of many diseases; thus, they serve as potential biomarkers for …

[HTML][HTML] Altered O-glycomes of Renal Brush-Border Membrane in Model Rats with Chronic Kidney Diseases

A Yu, J Zhao, J Zhong, J Wang, SPS Yadav… - Biomolecules, 2021 - mdpi.com
Chronic kidney disease (CKD) is defined as a decrease in renal function or glomerular
filtration rate (GFR), and proteinuria is often present. Proteinuria increases with age and can …