Targeting inflammation in hypertension
A Deussen, I Kopaliani - Current opinion in nephrology and …, 2023 - journals.lww.com
Although immunomodulation may be advantageous as a causal therapy in hypertension,
targeting immune networks rather than single interleukins appears of major importance …
targeting immune networks rather than single interleukins appears of major importance …
Inflammasomes in Atherosclerosis—From Pathophysiology to Treatment
Atherosclerosis, a chronic inflammatory disease characterized by arterial plaque
accumulation, remains a significant global health challenge. In recent years …
accumulation, remains a significant global health challenge. In recent years …
The role of dietary magnesium deficiency in inflammatory hypertension
A Pitzer Mutchler, L Huynh, R Patel, T Lam… - Frontiers in …, 2023 - frontiersin.org
Nearly 30% of adults consume less than the estimated average daily requirement of
magnesium (Mg2+), and commonly used medications, such as diuretics, promote Mg2+ …
magnesium (Mg2+), and commonly used medications, such as diuretics, promote Mg2+ …
Inflammatory mechanisms in heart failure with preserved ejection fraction
D Daou, TG Gillette, JA Hill - Physiology, 2023 - journals.physiology.org
Heart failure with preserved ejection fraction (HFpEF) is now the most common form of heart
failure and a significant public health concern for which limited effective therapies exist …
failure and a significant public health concern for which limited effective therapies exist …
Mechanisms of vascular inflammation and potential therapeutic targets: a position paper from the ESH Working Group on small arteries
FJ Rios, C de Ciuceis, G Georgiopoulos, A Lazaridis… - …, 2024 - Am Heart Assoc
Inflammatory responses in small vessels play an important role in the development of
cardiovascular diseases, including hypertension, stroke, and small vessel disease. This …
cardiovascular diseases, including hypertension, stroke, and small vessel disease. This …
Angiotensin II modulates calcium/phosphate excretion in experimental model of hypertension: Focus on bone
G Castoldi, R Carletti, S Ippolito, I Villa, B Palmisano… - Biomedicines, 2022 - mdpi.com
A link between hypertension and long-term bone health has been suggested. The aim of this
study was to investigate the effects of chronic angiotensin II administration on urinary …
study was to investigate the effects of chronic angiotensin II administration on urinary …
Resolution of inflammation, an active process to restore the immune microenvironment balance: A novel drug target for treating arterial hypertension
J Zhang, S Liu, W Ding, J Wan, JJ Qin… - Ageing Research Reviews, 2024 - Elsevier
The resolution of inflammation, the other side of the inflammatory response, is defined as an
active and highly coordinated process that promotes the restoration of immune …
active and highly coordinated process that promotes the restoration of immune …
Lactate dehydrogenase A (LDHA)-mediated lactate generation promotes pulmonary vascular remodeling in pulmonary hypertension
D Wu, S Wang, F Wang, Q Zhang, Z Zhang… - Journal of Translational …, 2024 - Springer
Background High levels of lactate are positively associated with prognosis and mortality in
pulmonary hypertension (PH). Lactate dehydrogenase A (LDHA) is a key enzyme for the …
pulmonary hypertension (PH). Lactate dehydrogenase A (LDHA) is a key enzyme for the …
A protective erythropoietin evolutionary landscape, NLRP3 inflammasome regulation, and multisystem inflammatory syndrome in children
KI Papadopoulos, A Papadopoulou, TC Aw - Human Cell, 2023 - Springer
The low incidence of pediatric severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2) infection and the associated multisystem inflammatory syndrome (MIS-C) lack a unifying …
2) infection and the associated multisystem inflammatory syndrome (MIS-C) lack a unifying …
The potential role of connexins in the pathogenesis of atherosclerosis
K Kiełbowski, E Bakinowska, A Pawlik - International Journal of Molecular …, 2023 - mdpi.com
Connexins (Cx) are members of a protein family which enable extracellular and intercellular
communication through hemichannels and gap junctions (GJ), respectively. Cx take part in …
communication through hemichannels and gap junctions (GJ), respectively. Cx take part in …