Wall shear stress–an important determinant of endothelial cell function and structure–in the arterial system in vivo: discrepancies with theory

RS Reneman, T Arts, APG Hoeks - Journal of vascular research, 2006 - karger.com
It has been well established that wall shear stress is an important determinant of endothelial
cell function and gene expression as well as of its structure. There is increasing evidence …

Biomechanics of the cardiovascular system: the aorta as an illustratory example

GS Kassab - Journal of the Royal Society Interface, 2006 - royalsocietypublishing.org
Biomechanics relates the function of a physiological system to its structure. The objective of
biomechanics is to deduce the function of a system from its geometry, material properties …

A machine-learning approach for computation of fractional flow reserve from coronary computed tomography

L Itu, S Rapaka, T Passerini… - Journal of applied …, 2016 - journals.physiology.org
Fractional flow reserve (FFR) is a functional index quantifying the severity of coronary artery
lesions and is clinically obtained using an invasive, catheter-based measurement. Recently …

Prediction of 3D Cardiovascular hemodynamics before and after coronary artery bypass surgery via deep learning

G Li, H Wang, M Zhang, S Tupin, A Qiao, Y Liu… - Communications …, 2021 - nature.com
The clinical treatment planning of coronary heart disease requires hemodynamic
parameters to provide proper guidance. Computational fluid dynamics (CFD) is gradually …

Haemodynamics-driven developmental pruning of brain vasculature in zebrafish

Q Chen, L Jiang, C Li, D Hu, J Bu, D Cai, J Du - 2012 - journals.plos.org
The brain blood vasculature consists of a highly ramified vessel network that is tailored to
meet its physiological functions. How the brain vasculature is formed has long been …

[图书][B] Applied mathematical models in human physiology

The purpose of this book is to study mathematical models of human physiology. The book is
a result of work by Math-Tech (in Copenhagen, Denmark) and the BioMath group at the …

Synthetic data-driven hemodynamic determination in medical imaging

LM Itu, T Passerini, S Rapaka, P Sharma… - US Patent …, 2016 - Google Patents
In hemodynamic determination in medical imaging, the clas sifier is trained from Synthetic
data rather than relying on training data from other patients. A computer model (in silico) …

Scaling laws of vascular trees: of form and function

GS Kassab - American Journal of Physiology-Heart and …, 2006 - journals.physiology.org
The branching pattern and vascular geometry of biological tree structure are complex. Here
we show that the design of all vascular trees for which there exist morphometric data in the …

On the design of the coronary arterial tree: a generalization of Murray's law

Y Zhou, GS Kassab, S Molloi - Physics in Medicine & Biology, 1999 - iopscience.iop.org
Murray's law has been generalized to provide morphometric relationships among various
subtrees as well as between a feeding segment and the subtree it perfuses. The equivalent …

Wall shear stress as measured in vivo: consequences for the design of the arterial system

RS Reneman, APG Hoeks - Medical & biological engineering & computing, 2008 - Springer
Based upon theory, wall shear stress (WSS), an important determinant of endothelial
function and gene expression, has been assumed to be constant along the arterial tree and …