A-to-I RNA editing—immune protector and transcriptome diversifier
E Eisenberg, EY Levanon - Nature Reviews Genetics, 2018 - nature.com
Modifications of RNA affect its function and stability. RNA editing is unique among these
modifications because it not only alters the cellular fate of RNA molecules but also alters …
modifications because it not only alters the cellular fate of RNA molecules but also alters …
The pilocarpine model of mesial temporal lobe epilepsy: Over one decade later, with more rodent species and new investigative approaches
M Lévesque, G Biagini, M de Curtis… - Neuroscience & …, 2021 - Elsevier
Fundamental work on the mechanisms leading to focal epileptic discharges in mesial
temporal lobe epilepsy (MTLE) often rests on the use of rodent models in which an initial …
temporal lobe epilepsy (MTLE) often rests on the use of rodent models in which an initial …
Investigating RNA editing in deep transcriptome datasets with REDItools and REDIportal
RNA editing is a widespread post-transcriptional mechanism able to modify transcripts
through insertions/deletions or base substitutions. It is prominent in mammals, in which …
through insertions/deletions or base substitutions. It is prominent in mammals, in which …
The evolution and adaptation of A-to-I RNA editing
AL Yablonovitch, P Deng, D Jacobson, JB Li - PLoS genetics, 2017 - journals.plos.org
Adenosine-to-inosine (A-to-I) RNA editing is an important post-transcriptional modification
that affects the information encoded from DNA to RNA to protein. RNA editing can generate …
that affects the information encoded from DNA to RNA to protein. RNA editing can generate …
The Q/R editing site of AMPA receptor GluA2 subunit acts as an epigenetic switch regulating dendritic spines, neurodegeneration and cognitive deficits in Alzheimer's …
Background RNA editing at the Q/R site of GluA2 occurs with~ 99% efficiency in the healthy
brain, so that the majority of AMPARs contain GluA2 (R) instead of the exonically encoded …
brain, so that the majority of AMPARs contain GluA2 (R) instead of the exonically encoded …
The cell line A-to-I RNA editing catalogue
Abstract Adenosine-to-inosine (A-to-I) RNA editing is a common post transcriptional
modification. It has a critical role in protecting against false activation of innate immunity by …
modification. It has a critical role in protecting against false activation of innate immunity by …
CircHivep2 contributes to microglia activation and inflammation via miR‐181a‐5p/SOCS2 signalling in mice with kainic acid‐induced epileptic seizures
G Xiaoying, M Guo, L Jie, Z Yanmei… - Journal of Cellular …, 2020 - Wiley Online Library
Epilepsy is a chronic brain disease characterized by recurrent seizures. Circular RNA
(circRNA) is a novel family of endogenous non‐coding RNAs that have been proposed to …
(circRNA) is a novel family of endogenous non‐coding RNAs that have been proposed to …
Transcriptome-wide profiling of A-to-I RNA editing by Slic-Seq
Abstract Adenosine-to-inosine (A-to-I) RNA editing is a post-transcriptional processing event
involved in diversifying the transcriptome and is responsible for various biological …
involved in diversifying the transcriptome and is responsible for various biological …
Increased RNA editing in maternal immune activation model of neurodevelopmental disease
The etiology of major neurodevelopmental disorders such as schizophrenia and autism is
unclear, with evidence supporting a combination of genetic factors and environmental …
unclear, with evidence supporting a combination of genetic factors and environmental …
A multi-sample approach increases the accuracy of transcript assembly
Transcript assembly from RNA-seq reads is a critical step in gene expression and
subsequent functional analyses. Here we present PsiCLASS, an accurate and efficient …
subsequent functional analyses. Here we present PsiCLASS, an accurate and efficient …