Norepinephrine (NE) is a major monoamine neurotransmitter that has widespread effects
across multiple brain areas to regulate arousal and stress responses. The underlying …

It was long thought that the prototypical centrally acting antihypertensive drug clonidine
lowers sympathetic tone by activating α2-adrenoceptors in the brain stem. Supported by the …

To assess the influence of exercise training on the growth hormone (GH) response to acute
exercise, six untrained males completed a 20-min, high-intensity, constant-load exercise test …

The classic concept of how pituitary GH is regulated by somatostatin and GHRH has
changed in recent years, following the discovery of peripheral hormones involved in the …

STUDY OBJECTIVE: To evaluate the capacity of dexmedetomidine (DEX), an α2 adrenergic
agonist drug, as a substitute for remifentanil (REM), a potent opioid, in total intravenous …

The episodic secretion of growth hormone(GH) depends on the rhythmic alternation in the
hypothalamic release of GHRH and somatostatin(SS) into the hypophyseal portal system. In …

Evidence supports that hyperactivity of the hypothalamic–pituitary–adrenal axis has a pivotal
role in the psychobiology of severe depression. The present study aimed at assessing …

The roles of hypothalamic growth hormone-releasing hormone (GHRH) and of somatostatin
(SRIF) in pharmacologically stimulated growth hormone (GH) secretion in humans are …

BACKGROUND: Numerous interactions between the brainstem locus coeruleus system and
the HPA axis have been shown in experimental animals. This relationship is less well …

This study was designed to compare growth hormone, cortisol and prolactin responses to
physical exercise in depressed patients and healthy comparison subjects. Patients fulfilled …