Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update

RB Panerai, P Brassard, JS Burma… - Journal of Cerebral …, 2023 - journals.sagepub.com
Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in
response to changes in perfusion pressure. Due to the challenges of measuring intracranial …

Quantification of dynamic cerebral autoregulation: welcome to the jungle!

P Brassard, MA Roy, JS Burma, L Labrecque… - Clinical Autonomic …, 2023 - Springer
Purpose Patients with dysautonomia often experience symptoms such as dizziness,
syncope, blurred vision and brain fog. Dynamic cerebral autoregulation, or the ability of the …

The effect of hypercapnia on the directional sensitivity of dynamic cerebral autoregulation and the influence of age and sex

RB Panerai, A Davies, RH Clough… - Journal of Cerebral …, 2024 - journals.sagepub.com
The cerebral circulation responds differently to increases in mean arterial pressure (MAP),
compared to reductions in MAP. We tested the hypothesis that this directional sensitivity is …

Directional sensitivity of dynamic cerebral autoregulation during spontaneous fluctuations in arterial blood pressure at rest

RB Panerai, SC Barnes, AP Batterham… - Journal of Cerebral …, 2023 - journals.sagepub.com
Directional sensitivity, the more efficient response of cerebral autoregulation to increases,
compared to decreases, in mean arterial pressure (MAP), has been demonstrated with …

Directional sensitivity of the cerebral pressure–flow relationship in young healthy individuals trained in endurance and resistance exercise

MA Roy, L Labrecque, BG Perry, S Korad… - Experimental …, 2022 - Wiley Online Library
New Findings What is the central question of this study? Does habitual exercise modality
affect the directionality of the cerebral pressure–flow relationship? What is the main finding …

Circadian and diurnal regulation of cerebral blood flow

AJS Webb, EB Klerman, ET Mandeville - Circulation Research, 2024 - Am Heart Assoc
Circadian and diurnal variation in cerebral blood flow directly contributes to the diurnal
variation in the risk of stroke, either through factors that trigger stroke or due to impaired …

A systematic review, meta-analysis, and meta-regression amalgamating the driven approaches used to quantify dynamic cerebral autoregulation

JS Burma, MA Roy, CM Kennedy… - Journal of Cerebral …, 2024 - journals.sagepub.com
Numerous driven techniques have been utilized to assess dynamic cerebral autoregulation
(dCA) in healthy and clinical populations. The current review aimed to amalgamate this …

Unraveling diurnal and technical variability in cerebral hemodynamics from neurovascular 4D-Flow MRI

LA Rivera-Rivera, GS Roberts, A Peret… - Journal of Cerebral …, 2024 - journals.sagepub.com
Neurovascular 4D-Flow MRI enables non-invasive evaluation of cerebral hemodynamics
including measures of cerebral blood flow (CBF), vessel pulsatility index (PI), and cerebral …

Point/counterpoint: we should take the direction of blood pressure change into consideration for dynamic cerebral autoregulation quantification

L Labrecque, JD Smirl, YC Tzeng… - Journal of Cerebral …, 2022 - journals.sagepub.com
Accumulating evidence suggests asymmetrical responses of cerebral blood flow during
large transient changes in mean arterial pressure. Specifically, the augmentation in cerebral …

Influence of high‐intensity interval training to exhaustion on the directional sensitivity of the cerebral pressure‐flow relationship in young endurance‐trained men

F Abbariki, MA Roy, L Labrecque… - Physiological …, 2022 - Wiley Online Library
We previously reported subtle dynamic cerebral autoregulation (dCA) alterations following 6
weeks of high‐intensity interval training (HIIT) to exhaustion using transfer function analysis …