Recent progress in 1H-1, 2, 3-triazoles as potential antifungal agents
The need to overcome ever-increasing cases of antifungal resistance and circumvent side
effects and drug interactions related to currently available drugs has impelled the demand to …
effects and drug interactions related to currently available drugs has impelled the demand to …
Chalcones: Versatile intermediates in heterocyclic synthesis
YN Nayak, SL Gaonkar, M Sabu - Journal of Heterocyclic …, 2023 - Wiley Online Library
Chalcones are a fascinating and well‐studied group of organic molecules. Synthesis of
chalcones has been one of the essential areas of organic synthesis over the last few …
chalcones has been one of the essential areas of organic synthesis over the last few …
New oxadiazole/triazole derivatives with antimicrobial and antioxidant properties
In the search for new antimicrobial agents, we synthesized a new series of oxadiazole and
triazole derivatives. The series of N-(benzothiazol-2-yl)-2-{{5-[(2-chlorophenoxy) methyl]-1 …
triazole derivatives. The series of N-(benzothiazol-2-yl)-2-{{5-[(2-chlorophenoxy) methyl]-1 …
[HTML][HTML] Design, synthesis, biological evaluation and in silico studies of novel 1, 2, 3-triazole linked benzoxazine-2, 4-dione conjugates as potent antimicrobial …
MB Hammouda, I Ahmad, A Hamdi, A Dbeibia… - Arabian Journal of …, 2022 - Elsevier
In an attempt to rationalize the search for new potential anti-inflammatory and anti-infection
agents, a new series of 1, 4-and 1, 5-disubstituted 1, 2, 3-triazoles linked benzoxazine …
agents, a new series of 1, 4-and 1, 5-disubstituted 1, 2, 3-triazoles linked benzoxazine …
New bis-and tetrakis-1, 2, 3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants
In this study, a series of bis–and tetrakis–1, 2, 3–triazole derivatives were synthesized using
copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry in 73–95% yield. The …
copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry in 73–95% yield. The …
Triazole based novel molecules as potential therapeutic agents: Synthesis, characterization, biological evaluation, in-silico ADME profiling and molecular docking …
In this study, eight new compounds (7a-h) based on triazole compounds containing ester
groups were synthesized with high yields. The structures of the synthesized compounds (7a …
groups were synthesized with high yields. The structures of the synthesized compounds (7a …
Novel hybrid structures based on 4-Chlorobenzenesulfonyl and 1, 2, 3-triazoles: Synthesis, in vitro biological activities and in silico studies
New hybrid structures containing 4-chlorosulfonamide and 1, 2, 3-triazole units were
designed and synthesized. Antioxidant, cholinesterase (AChE and BuChE) and anticancer …
designed and synthesized. Antioxidant, cholinesterase (AChE and BuChE) and anticancer …
Design and synthesis of 1, 4-disubstituted 1, 2, 3-triazoles: Biological evaluation, in silico molecular docking and ADME screening
In this study, propargyl compounds were synthesized from 4-hydroxybenzaldehyde and 3‑
methoxy-4-hydroxybenzaldehyde (2a-2b). As a result of click reactions of synthesized …
methoxy-4-hydroxybenzaldehyde (2a-2b). As a result of click reactions of synthesized …
Synthesis, antimalarial and antioxidant activity of coumarin appended 1, 4-disubstituted 1, 2, 3-triazoles
CP Kaushik, M Chahal - Monatshefte für Chemie-Chemical Monthly, 2021 - Springer
A series of coumarin appended triazole hybrids of biotic interest was synthesized through
click chemistry approach from the coumarin based terminal alkynes and aromatic azides. All …
click chemistry approach from the coumarin based terminal alkynes and aromatic azides. All …
Synthesis of thiazolidine-2, 4-dione tethered 1, 2, 3-triazoles as α-amylase inhibitors: In vitro approach coupled with QSAR, molecular docking, molecular dynamics …
A new series of thiazolidine-2, 4-dione tethered 1, 2, 3-triazole derivatives were designed,
synthesized and screened for their α-amylase inhibitory potential employing in vitro and in …
synthesized and screened for their α-amylase inhibitory potential employing in vitro and in …