Toxoplasma secretory granules: one population or more?
C Mercier, MF Cesbron-Delauw - Trends in parasitology, 2015 - cell.com
In Toxoplasma gondii, dense granules are known as the storage secretory organelles of the
so-called GRA proteins (for dense granule proteins), which are destined to the …
so-called GRA proteins (for dense granule proteins), which are destined to the …
Protein export into malaria parasite–infected erythrocytes: mechanisms and functional consequences
NJ Spillman, JR Beck… - Annual review of …, 2015 - annualreviews.org
Phylum Apicomplexa comprises a large group of obligate intracellular parasites of high
medical and veterinary importance. These organisms succeed intracellularly by effecting …
medical and veterinary importance. These organisms succeed intracellularly by effecting …
Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites
The eukaryotic phylum Apicomplexa encompasses thousands of obligate intracellular
parasites of humans and animals with immense socio-economic and health impacts. We …
parasites of humans and animals with immense socio-economic and health impacts. We …
In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis
SM Nadipuram, EW Kim, AA Vashisht, AH Lin, HN Bell… - MBio, 2016 - Am Soc Microbiol
Toxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates
within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite …
within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite …
The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells
A Curt‐Varesano, L Braun, C Ranquet… - Cellular …, 2016 - Wiley Online Library
Toxoplasma gondii and Plasmodium species are obligatory intracellular parasites that
export proteins into the infected cells in order to interfere with host‐signalling pathways …
export proteins into the infected cells in order to interfere with host‐signalling pathways …
The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses
L Chen, DA Christian, JA Kochanowsky… - Journal of Experimental …, 2020 - rupress.org
The ability of Toxoplasma gondii to inject the rhoptry kinase ROP16 into host cells results in
the activation of the transcription factors STAT3 and STAT6, but it is unclear how these …
the activation of the transcription factors STAT3 and STAT6, but it is unclear how these …
[HTML][HTML] Recent advances in understanding apicomplexan parasites
F Seeber, S Steinfelder - F1000Research, 2016 - ncbi.nlm.nih.gov
Intracellular single-celled parasites belonging to the large phylum Apicomplexa are amongst
the most prevalent and morbidity-causing pathogens worldwide. In this review, we highlight …
the most prevalent and morbidity-causing pathogens worldwide. In this review, we highlight …
Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity
HL Mercer, LM Snyder, CM Doherty, BA Fox… - PLoS …, 2020 - journals.plos.org
The apicomplexan Toxoplasma gondii induces strong protective immunity dependent upon
recognition by Toll-like receptors (TLR) 11 and 12 operating in conjunction with MyD88 in …
recognition by Toll-like receptors (TLR) 11 and 12 operating in conjunction with MyD88 in …
Seizing control: How dense granule effector proteins enable Toxoplasma to take charge
MW Panas, JC Boothroyd - Molecular microbiology, 2021 - Wiley Online Library
Control of the host cell is crucial to the Apicomplexan parasite, Toxoplasma gondii, while it
grows intracellularly. To achieve this goal, these single‐celled eukaryotes export a series of …
grows intracellularly. To achieve this goal, these single‐celled eukaryotes export a series of …
Toxoplasma's ways of manipulating the host transcriptome via secreted effectors
MA Hakimi, A Bougdour - Current opinion in microbiology, 2015 - Elsevier
The obligate intracellular parasite Toxoplasma gondii strikes a subtle balance with the host
immune system that not only prevents host death but also promotes parasite persistence …
immune system that not only prevents host death but also promotes parasite persistence …