Although mutations in human gonadotrophin and gonadotrophin receptor genes are rare,
they have greatly elucidated the physiology and pathophysiology of gonadotrophin action …

Gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone, and luteinizing
hormone orchestrate the reproduction cycle and regulate the sex steroid secretion from the …

Thirty-nine adult light horse mares, geldings, and stallions were used in two experiments to
assess the pituitary hormone and insulin responses to infusions of arginine, aspartic acid …

Chronic renal failure is associated with delayed puberty and hypogonadism. To investigate
the mechanisms subserving the reported reduced pulsatile release of gonadotropin …

D-Cycloserine, a partial agonist of the glycine recognition site of the N-methyl-D-aspartate
(NMDA) receptor, may serve as a probe for human cerebral NMDA receptor function. Since …

Brainstem catecholaminergic neurons are believed to play an important role in the activation
of luteinising hormone-releasing hormone (LHRH) neurons on the afternoon of proestrus …

Excitatory amino acids, such as glutamate, exert a profound stimulatory effect on the
reproductive axis of several mammals. Although glutamate receptor agonists stimulate …

About 1000 hypothalamic neurons synthesize and release gonadotropin-releasing hormone
(GnRH), the master molecule of reproduction in all mammals. At the level of the median …

In this paper, we report the endogenous expression of functional α2-adrenergic receptors
(α2-ARs) in the immortalized hypothalamic cell line, GT1. Membranes from GT1 cells …

The stimulatory influence of N-methyl-d-aspartate (NMDA), a glutamate receptor agonist, on
LH secretion is well established in several mammalian species including the rhesus …