Angiogenesis and lymphangiogenesis in corneal transplantation–A review

W Zhong, M Montana, SM Santosa, ID Isjwara… - Survey of …, 2018 - Elsevier
Corneal transplantation has been proven effective for returning the gift of sight to those
affected by corneal disorders such as opacity, injury, and infections that are a leading cause …

Lymphatic trafficking in the eye: modulation of lymphatic trafficking to promote corneal transplant survival

Y Hou, F Bock, D Hos, C Cursiefen - Cells, 2021 - mdpi.com
(Lymph) angiogenesis into the cornea prior to and after corneal transplantation is a critical
risk factor for allograft rejection. Lymphatic vessels even more than blood vessels seem …

Atorvastatin-loaded peptide amphiphiles against corneal neovascularization

E Sánchez-López, MJ Gómara, I Haro - Nanomedicine, 2023 - Taylor & Francis
Background: Corneal neovascularization is a sight-threatening disease. It can be treated
using antiangiogenic and anti-inflammatory compounds. Therefore, atorvastatin (ATV) …

Corneal Opacity in the United States: An American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight) Study

RB Singh, TH Dohlman, A Ivanov, N Hall, C Ross… - Ophthalmology, 2024 - Elsevier
Purpose This study assesses the case frequencies, underlying causes, and vision outcomes
in patients with a diagnosis of corneal opacity in the United States. Design Retrospective …

Lipid keratopathy: a review of pathophysiology, differential diagnosis, and management

MGN Hall, M Moshirfar, A Amin-Javaheri… - Ophthalmology and …, 2020 - Springer
Lipid keratopathy is a disease in which fat deposits accumulate in the cornea, leading to
opacification and decrease of visual acuity. This condition can be idiopathic without signs of …

LncRNA Meg3 knockdown reduces corneal neovascularization and VEGF-induced vascular endothelial angiogenesis via SDF-1/CXCR4 and Smad2/3 pathway

T Shen, Y Wu, W Cai, H Jin, D Yu, Q Yang… - Experimental Eye …, 2022 - Elsevier
The crucial effect of vascular endothelial growth factor (VEGF)-induced vascular
angiogenesis has been well known in corneal neovascularization (CNV). This research …

Targeting corneal inflammation by gene therapy: Emerging strategies for keratitis

J Torrecilla, A del Pozo-Rodriguez… - Experimental Eye …, 2018 - Elsevier
Inflammation is the underlying process of several diseases within the eye, specifically in the
cornea. Current treatment options for corneal inflammation or keratitis, and related …

Zeb1 promotes corneal neovascularization by regulation of vascular endothelial cell proliferation

L Jin, Y Zhang, W Liang, X Lu, N Piri, W Wang… - Communications …, 2020 - nature.com
Angiogenesis is required for tissue repair; but abnormal angiogenesis or neovascularization
(NV) causes diseases in the eye. The avascular status in the cornea is a prerequisite for …

Functional peptide-loaded gelatin nanoparticles as eyedrops for cornea neovascularization treatment

YC Chu, HW Fang, YY Wu, YJ Tang… - International journal …, 2023 - Taylor & Francis
Background Corneal neovascularization (NV) is a process of abnormal vessel growth into
the transparent cornea from the limbus and can disturb the light passing through the cornea …

Therapeutic potential of topical administration of siRNAs against HIF-1α for corneal neovascularization

A Peral, J Mateo, CO Dominguez-Godinez… - Experimental Eye …, 2022 - Elsevier
Given the implications of the problem of neovascularization on ocular health, as well as the
growth in the number of cases, the purpose of the present study has been testing the efficacy …