Nicotinic acetylcholine, serotonin type 3, γ-amminobutyric acid type A, and glycine receptors
are major players of human neuronal communication. They belong to the family of …

Pentameric ligand‐gated ion channels (pLGICs) mediate fast neurotransmission in the
nervous system. Their dysfunction is associated with psychiatric, neurological and …

Plants rely on systemic signalling mechanisms to establish whole-body defence in response
to insect and nematode attacks. GLUTAMATE RECEPTOR-LIKE (GLR) genes have been …

Several cell types experience repetitive mechanical stimuli, including vein endothelial cells
during pulsating blood flow, inner ear hair cells upon sound exposure, and skin cells and …

Cys-loop neurotransmitter-gated ion channels are vital for communication throughout the
nervous system. Following activation, these receptors enter into a desensitized state in …

Neurodevelopmental processes of pluripotent cells, such as proliferation and differentiation,
are influenced by external natural forces. Despite the presence of biogenic magnetite …

The olfactory bulb (OB) is central to the sense of smell, as it is the site of the first synaptic
relay involved in the processing of odor information. Odor sensations are first transduced by …

Key points Cation–chloride cotransporters (CCCs) play a critical role in controlling the
efficacy and polarity of GABAA receptor (GABAAR)‐mediated transmission in the brain, yet …

The determination of structural models of the various stable states of an ion channel is a key
step toward the characterization of its conformational dynamics. In the case of nicotinic-type …

The brain's extracellular matrix (ECM) is crucial for neural circuit functionality, synaptic
plasticity, and learning. While the role of the ECM in excitatory synapses has been …