Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis

D Chaudhuri, K Sasaki, A Karkar, S Sharif… - Intensive care …, 2021 - Springer
Purpose Corticosteroids are now recommended for patients with severe COVID-19 including
those with COVID-related ARDS. This has generated renewed interest regarding whether …

Pharmacological agents for adults with acute respiratory distress syndrome

SR Lewis, MW Pritchard, CM Thomas… - Cochrane Database of …, 2019 - cochranelibrary.com
Background Acute respiratory distress syndrome (ARDS) is a life‐threatening condition
caused by direct or indirect injury to the lungs. Despite improvements in clinical …

Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial

J Villar, C Ferrando, D Martínez, A Ambrós… - The Lancet …, 2020 - thelancet.com
Background There is no proven specific pharmacological treatment for patients with the
acute respiratory distress syndrome (ARDS). The efficacy of corticosteroids in ARDS …

Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care …

D Annane, SM Pastores, B Rochwerg, W Arlt… - Intensive care …, 2017 - Springer
Objective To update the 2008 consensus statements for the diagnosis and management of
critical illness-related corticosteroid insufficiency (CIRCI) in adult and pediatric patients …

An update on management of adult patients with acute respiratory distress syndrome: an official American Thoracic Society clinical practice guideline

N Qadir, S Sahetya, L Munshi, C Summers… - American journal of …, 2024 - atsjournals.org
Background: This document updates previously published Clinical Practice Guidelines for
the management of patients with acute respiratory distress syndrome (ARDS), incorporating …

Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection

YM Arabi, AA Arifi, HH Balkhy, H Najm… - Annals of internal …, 2014 - acpjournals.org
Background: Since September 2012, 170 confirmed infections with Middle East respiratory
syndrome coronavirus (MERS-CoV) have been reported to the World Health Organization …

Open lung approach for the acute respiratory distress syndrome: a pilot, randomized controlled trial

RM Kacmarek, J Villar, D Sulemanji… - Critical care …, 2016 - journals.lww.com
Objective: The open lung approach is a mechanical ventilation strategy involving lung
recruitment and a decremental positive end-expiratory pressure trial. We compared the …

Pharmacological principles guiding prolonged glucocorticoid treatment in ARDS

GU Meduri, D Annane, M Confalonieri… - Intensive care …, 2020 - Springer
Current literature addressing the pharmacological principles guiding glucocorticoid (GC)
administration in ARDS is scant. This paucity of information may have led to the …

Prolonged glucocorticoid treatment is associated with improved ARDS outcomes: analysis of individual patients' data from four randomized trials and trial-level meta …

GU Meduri, L Bridges, MC Shih, PE Marik… - Intensive care …, 2016 - Springer
Purpose To investigate the effect of prolonged glucocorticoid treatment for patients with
acute respiratory distress syndrome (ARDS). Methods We conducted two sets of intention-to …

Definitions and pathophysiology of vasoplegic shock

S Lambden, BC Creagh-Brown, J Hunt, C Summers… - Critical Care, 2018 - Springer
Vasoplegia is the syndrome of pathological low systemic vascular resistance, the dominant
clinical feature of which is reduced blood pressure in the presence of a normal or raised …