Sex‐specific aging in animals: perspective and future directions

AM Bronikowski, RP Meisel, PR Biga, JR Walters… - Aging …, 2022 - Wiley Online Library
Sex differences in aging occur in many animal species, and they include sex differences in
lifespan, in the onset and progression of age‐associated decline, and in physiological and …

[HTML][HTML] Transcriptomes of aging brain, heart, muscle, and spleen from female and male African turquoise killifish

A Xu, BB Teefy, RJ Lu, S Nozownik, AM Tyers… - Scientific Data, 2023 - nature.com
The African turquoise killifish is an emerging vertebrate model organism with great potential
for aging research due to its naturally short lifespan. Thus far, turquoise killifish aging …

Identification of protein aggregates in the aging vertebrate brain with prion-like and phase-separation properties

I Harel, YR Chen, I Ziv, PP Singh, D Heinzer… - Cell reports, 2024 - cell.com
Protein aggregation, which can sometimes spread in a prion-like manner, is a hallmark of
neurodegenerative diseases. However, whether prion-like aggregates form during normal …

Rapid and precise genome engineering in a naturally short-lived vertebrate

CN Bedbrook, RD Nath, R Nagvekar, K Deisseroth… - Elife, 2023 - elifesciences.org
The African turquoise killifish is a powerful vertebrate system to study complex phenotypes
at scale, including aging and age-related disease. Here, we develop a rapid and precise …

[HTML][HTML] Hallmarks of Aging: A User's Guide for Comparative Biologists

PR Biga, JE Duan, TE Young, JR Marks… - Ageing Research …, 2024 - Elsevier
Since the first description of a set of characteristics of aging as so-called hallmarks or pillars
in 2013/2014, these characteristics have served as guideposts for the research in aging …

Breeding and reproduction of the African turquoise killifish Nothobranchius furzeri

J Chen, RC Khondker, A Brunet - Cold Spring Harbor …, 2023 - cshprotocols.cshlp.org
The successful breeding and reproduction of the African turquoise killifish Nothobranchius
furzeri in a controlled laboratory setting are required to establish this fish species as a model …

Starter feed for carnivorous species as a practical replacement of bloodworms for a vertebrate model organism in ageing, the turquoise killifish Nothobranchius furzeri

J Žák, K Roy, I Dyková, J Mráz… - Journal of Fish …, 2022 - Wiley Online Library
The absence of a controlled diet is unfortunate in a promising model organism for ageing,
the turquoise killifish (Nothobranchius furzeri Jubb, 1971). Currently captive N. furzeri are …

The African turquoise killifish: A scalable vertebrate model for aging and other complex phenotypes

F Boos, J Chen, A Brunet - Cold Spring Harbor Protocols, 2024 - cshprotocols.cshlp.org
Abstract The African turquoise killifish Nothobranchius furzeri is currently the shortest-lived
vertebrate that can be bred in captivity. Because of its short life span of only 4–6 months …

A framework for a low‐cost system of automated gate control in assays of spatial cognition in fishes

V Lucks, J Theine, MP Arteaga Avendaño… - Journal of Fish …, 2024 - Wiley Online Library
Automation of experimental setups is a promising direction in behavioral research because
it can facilitate the acquisition of data while increasing its repeatability and reliability. For …

Surviving on limited resources: effects of caloric restriction on growth, gene expression and gut microbiota in a species with male pregnancy (Hippocampus erectus)

FA Pappert, VA Wüst, CF Eguiguren, O Roth - bioRxiv, 2023 - biorxiv.org
The positive health effects of caloric restriction (CR) have been widely studied in a few
conventional model species, displaying typically conventional reproductive roles, with …