Circulating endocannabinoids: from whence do they come and where are they going?

CJ Hillard - Neuropsychopharmacology, 2018 - nature.com
The goal of this review is to summarize studies in which concentrations of circulating
endocannabinoids in humans have been examined in relationship to physiological …

Is there a “metabolic-mood syndrome”? A review of the relationship between obesity and mood disorders

RB Mansur, E Brietzke, RS McIntyre - Neuroscience & Biobehavioral …, 2015 - Elsevier
Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …

The endocannabinoid system: pivotal orchestrator of obesity and metabolic disease

W Mazier, N Saucisse, B Gatta-Cherifi… - Trends in Endocrinology & …, 2015 - cell.com
The endocannabinoid system (ECS) functions to adjust behavior and metabolism according
to environmental changes in food availability. Its actions range from the regulation of …

Care and feeding of the endocannabinoid system: a systematic review of potential clinical interventions that upregulate the endocannabinoid system

JM McPartland, GW Guy, V Di Marzo - PloS one, 2014 - journals.plos.org
Background The “classic” endocannabinoid (eCB) system includes the cannabinoid
receptors CB1 and CB2, the eCB ligands anandamide (AEA) and 2-arachidonoylglycerol (2 …

The gut microbiome, endocannabinoids and metabolic disorders

FA Iannotti, V Di Marzo - Journal of Endocrinology, 2021 - joe.bioscientifica.com
Two complex systems are emerging as being deeply involved in the control of energy
metabolism. The intestinal microbiota, with its warehouse of genes, proteins and small …

Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity

DA Argueta, NV DiPatrizio - Physiology & behavior, 2017 - Elsevier
The endocannabinoid system in the brain and periphery plays a major role in controlling
food intake and energy balance. We reported that tasting dietary fats was met with increased …

Mechanisms in endocrinology: endocannabinoids and metabolism: past, present and future

V Simon, D Cota - European journal of endocrinology, 2017 - academic.oup.com
The endocannabinoid system (ECS), including cannabinoid type 1 and type 2 receptors
(CB1R and CB2R), endogenous ligands called endocannabinoids and their related …

Multiple endocannabinoid-mediated mechanisms in the regulation of energy homeostasis in brain and peripheral tissues

I Ruiz de Azua, B Lutz - Cellular and molecular life sciences, 2019 - Springer
The endocannabinoid (eCB) system is widely expressed in many central and peripheral
tissues, and is involved in a plethora of physiological processes. Among these, activity of the …

The endocannabinoid system and appetite: relevance for food reward

G Jager, RF Witkamp - Nutrition research reviews, 2014 - cambridge.org
Mounting evidence substantiates the central role of the endocannabinoid system (ECS) in
the modulation of both homeostatic and hedonic elements of appetite and food intake …

Endocannabinoid signaling and food addiction

C D'Addario, MVM Di Bonaventura, M Pucci… - Neuroscience & …, 2014 - Elsevier
Overeating, frequently linked to an increasing incidence of overweight and obesity, has
become epidemic and one of the leading global health problems. To explain the …