No country for old antibiotics! Antimicrobial peptides (AMPs) as next-generation treatment for skin and soft tissue infection
In recent years, the unprecedented rise of bacterial antibiotic resistance together with the
lack of adequate therapies have made the treatment of skin infections and chronic wounds …
lack of adequate therapies have made the treatment of skin infections and chronic wounds …
Cell-penetrating peptides and transportan
Ü Langel - Pharmaceutics, 2021 - mdpi.com
In the most recent 25–30 years, multiple novel mechanisms and applications of cell-
penetrating peptides (CPP) have been demonstrated, leading to novel drug delivery …
penetrating peptides (CPP) have been demonstrated, leading to novel drug delivery …
Antimicrobial and amyloidogenic activity of peptides. Can antimicrobial peptides be used against SARS-CoV-2?
SR Kurpe, SY Grishin, AK Surin, AV Panfilov… - International Journal of …, 2020 - mdpi.com
At present, much attention is paid to the use of antimicrobial peptides (AMPs) of natural and
artificial origin to combat pathogens. AMPs have several points that determine their …
artificial origin to combat pathogens. AMPs have several points that determine their …
MgrB Mutations and Altered Cell Permeability in Colistin Resistance in Klebsiella pneumoniae
There has been a resurgence in the clinical use of polymyxin antibiotics such as colistin due
to the limited treatment options for infections caused by carbapenem-resistant …
to the limited treatment options for infections caused by carbapenem-resistant …
Bacterial outer-membrane-mimicking giant unilamellar vesicle model for detecting antimicrobial permeability
The construction of bacterial outer membrane models with native lipids like
lipopolysaccharide (LPS) is a barrier to understanding antimicrobial permeability at the …
lipopolysaccharide (LPS) is a barrier to understanding antimicrobial permeability at the …
Effects of membrane potentials on the electroporation of giant unilamellar vesicles
Living organisms maintain a resting membrane potential, which plays an important role in
various biophysical and biological processes. In the context of medical applications …
various biophysical and biological processes. In the context of medical applications …
Synergistic Inhibition of Plantaricin E/F and Lactic Acid Against Aeromonas hydrophila LPL-1 Reveals the Novel Potential of Class IIb Bacteriocin
Y Wang, Y Wei, N Shang, P Li - Frontiers in Microbiology, 2022 - frontiersin.org
Plantaricin E/F (PlnEF) is a pair of two-component class IIb bacteriocin produced by lactic
acid bacteria. PlnEF commonly displays potent antimicrobial activity against certain Gram …
acid bacteria. PlnEF commonly displays potent antimicrobial activity against certain Gram …
Effects of polyethylene glycol-grafted phospholipid on the anionic magnetite nanoparticles-induced deformation and poration in giant lipid vesicles
The hydrophilic polymer polyethylene glycol-grafted phospholipid has been used
extensively in the study of artificial vesicles, nanomedicine, and antimicrobial …
extensively in the study of artificial vesicles, nanomedicine, and antimicrobial …
Recent developments in the kinetics of ruptures of giant vesicles under constant tension
External tension in membranes plays a vital role in numerous physiological and
physicochemical phenomena. In this review, recent developments in the constant electric …
physicochemical phenomena. In this review, recent developments in the constant electric …
In vitro assays: friends or foes of cell-penetrating peptides
J Liu, S Afshar - International Journal of Molecular Sciences, 2020 - mdpi.com
The cell membrane is a complex and highly regulated system that is composed of lipid
bilayer and proteins. One of the main functions of the cell membrane is the regulation of cell …
bilayer and proteins. One of the main functions of the cell membrane is the regulation of cell …