Neural tissue engineering (NTE) is a rapidly progressing field that promises to address
several serious neurological conditions that are currently difficult to treat. Selecting the right …

Proper patterning of the nervous system requires that developing axons find appropriate
postsynaptic partners; this entails microns to meters of extension through an extracellular …

Currently there are no potential curative therapies that can improve the central nervous
system (CNS) regeneration after traumatic injuries or diseases. Indeed, the regeneration of …

Peripheral nerve injury (PNI) caused by trauma, chronic disease and other factors may lead
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …

A todo o pessoal do laboratório de Química Orgânica, de um modo especial à Cláudia e à
Lipa, à Joana Brás, ao João, ao Leandro, à Teresa, à Sónia, à Andreia e ao Flávio, pela …

Major obstacles in brain cancer treatment include the blood-tumor barrier (BTB), which limits
the access of most therapeutic agents, and quiescent tumor cells, which resist conventional …

A sort of composite hydrogel with good biocompatibility, suppleness, high conductivity, and
anti-inflammatory activity based on polyvinyl alcohol (PVA) and molybdenum …

Cofilin is best known for its ability to sever actin filaments and facilitate cytoskeletal recycling
inside of cells, but at higher concentrations in vitro, cofilin stabilizes a more flexible, hyper …

Although many details remain still elusive, it became increasingly evident in recent years
that mechanosensing of microenvironmental biophysical cues and subsequent …

Actin filaments and associated proteins undergo wave-like movement in various cell types.
Recent studies with cutting-edge analyses, including live-cell imaging, biophysical …