[HTML][HTML] Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug

S Procaccia, GM Lewitus, C Lipson Feder… - Frontiers in …, 2022 - frontiersin.org
Medical Cannabis and its major cannabinoids (−)-trans-Δ9-tetrahydrocannabinol (THC) and
cannabidiol (CBD) are gaining momentum for various medical purposes as their therapeutic …

[HTML][HTML] Neuroprotective and immunomodulatory action of the endocannabinoid system under neuroinflammation

LA Kasatkina, S Rittchen, EM Sturm - International Journal of Molecular …, 2021 - mdpi.com
Endocannabinoids (eCBs) are lipid-based retrograde messengers with a relatively short half-
life that are produced endogenously and, upon binding to the primary cannabinoid receptors …

[HTML][HTML] Cannabis consumption used by cancer patients during immunotherapy correlates with poor clinical outcome

G Bar-Sela, I Cohen, S Campisi-Pinto, GM Lewitus… - Cancers, 2020 - mdpi.com
Simple Summary Cannabis is widely used by patients with cancer to help with cancer
symptoms and treatment side effects. Though cannabis has immunomodulatory effects, and …

[HTML][HTML] SPME as a green sample-preparation technique for the monitoring of phytocannabinoids and endocannabinoids in complex matrices

K Woźniczka, P Konieczyński, A Plenis… - Journal of …, 2023 - Elsevier
The endocannabinoid system (ECS), particularly its signaling pathways and ligands, has
garnered considerable interest in recent years. Along with clinical work investigating the …

[HTML][HTML] Supercritical Carbon Dioxide Technology for Recovering Valuable Phytochemicals from Cannabis sativa L. and Valorization of Its Biomass for Food …

AC de Aguiar, R Vardanega, J Viganó, EK Silva - Molecules, 2023 - mdpi.com
Supercritical carbon dioxide (CO2) extraction techniques meet all-new consumer market
demands for health-promoting phytochemical compound-rich extracts produced from green …

Cannabinoids vs. whole metabolome: Relevance of cannabinomics in analyzing Cannabis varieties

PG Vásquez-Ocmín, G Marti, M Bonhomme… - Analytica chimica …, 2021 - Elsevier
Cannabis sativa has a long history of domestication both for its bioactive compounds and its
fibers. This has produced hundreds of varieties, usually characterized in the literature by …

[HTML][HTML] Beyond Δ9-tetrahydrocannabinol and cannabidiol: Chemical differentiation of cannabis varieties applying targeted and untargeted analysis

MC Monti, P Frei, S Weber, E Scheurer… - Analytical and …, 2022 - Springer
Cannabis sativa (C. sativa) is commonly chemically classified based on its Δ9-
tetrahydrocannabinol (THC) and cannabidiol (CBD) content ratios. However, the plant …

[HTML][HTML] The effect of orally administered δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on obesity parameters in mice

A Eitan, O Gover, L Sulimani, D Meiri… - International Journal of …, 2023 - mdpi.com
Prolonged cannabis users show a lower prevalence of obesity and associated
comorbidities. In rodent models, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) …

Decreased melanoma CSF-1 secretion by Cannabigerol treatment reprograms regulatory myeloid cells and reduces tumor progression

I Wyrobnik, M Steinberg, A Gelfand… - …, 2023 - Taylor & Francis
During solid tumor progression, the tumor microenvironment (TME) evolves into a highly
immunosuppressive milieu. Key players in the immunosuppressive environment are …

[HTML][HTML] The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury

S Vered, AS Beiser, L Sulimani, S Sznitman… - Alzheimer's Research & …, 2023 - Springer
Background Preclinical studies highlight the importance of endogenous cannabinoids
(endocannabinoids; eCBs) in neurodegeneration. Yet, prior observational studies focused …