The brain tumor microenvironment
NA Charles, EC Holland, R Gilbertson, R Glass… - Glia, 2012 - Wiley Online Library
High‐grade brain tumors are heterogeneous with respect to the composition of bona fide
tumor cells and with respect to a range of intermingling parenchymal cells. Glioblastomas …
tumor cells and with respect to a range of intermingling parenchymal cells. Glioblastomas …
The brain tumor microenvironment
NA Charles, EC Holland, R Gilbertson, R Glass… - Glia, 2011 - Wiley Online Library
High‐grade brain tumors are heterogeneous with respect to the composition of bona fide
tumors cells and with respect to a range of intermingling parenchymal cells. Glioblastomas …
tumors cells and with respect to a range of intermingling parenchymal cells. Glioblastomas …
MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo
MicroRNAs (miRNAs) are believed to have fundamental roles in tumorigenesis and have
great potential for the diagnosis and treatment of cancer. However, the roles of miRNAs in …
great potential for the diagnosis and treatment of cancer. However, the roles of miRNAs in …
LINC01638 lncRNA activates MTDH-Twist1 signaling by preventing SPOP-mediated c-Myc degradation in triple-negative breast cancer
L Luo, H Tang, L Ling, N Li, X Jia, Z Zhang, X Wang… - Oncogene, 2018 - nature.com
Breast cancer is a heterogeneous disease, and triple-negative breast cancer (TNBC)
continues to be a serious health problem. The potential involvement of lncRNAs in TNBC …
continues to be a serious health problem. The potential involvement of lncRNAs in TNBC …
Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression
BK Yoo, L Emdad, Z Su, A Villanueva… - The Journal of …, 2009 - Am Soc Clin Investig
Hepatocellular carcinoma (HCC) is a highly aggressive vascular cancer characterized by
diverse etiology, activation of multiple signal transduction pathways, and various gene …
diverse etiology, activation of multiple signal transduction pathways, and various gene …
Mechanism of ceftriaxone induction of excitatory amino acid transporter-2 expression and glutamate uptake in primary human astrocytes
SG Lee, ZZ Su, L Emdad, P Gupta, D Sarkar… - Journal of Biological …, 2008 - ASBMB
Glutamate is an essential neurotransmitter regulating brain functions. Excitatory amino acid
transporter (EAAT)-2 is one of the major glutamate transporters primarily expressed in …
transporter (EAAT)-2 is one of the major glutamate transporters primarily expressed in …
The multifaceted role of MTDH/AEG-1 in cancer progression
Cancer is the result of the progressive acquisition of multiple malignant traits through the
accumulation of genetic or epigenetic alterations. Recent studies have established a …
accumulation of genetic or epigenetic alterations. Recent studies have established a …
Astrocyte elevated gene-1 is a novel prognostic marker for breast cancer progression and overall patient survival
J Li, N Zhang, LB Song, WT Liao, LL Jiang… - Clinical cancer …, 2008 - AACR
Purpose: The present study was aimed at clarifying the expression of astrocyte elevated
gene-1 (AEG-1), one of the target genes of oncogenic Ha-ras, in breast cancer and its …
gene-1 (AEG-1), one of the target genes of oncogenic Ha-ras, in breast cancer and its …
Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer
B Zhang, XX Liu, JR He, CX Zhou, M Guo, M He… - …, 2011 - academic.oup.com
The role of miR-26a in carcinogenesis appears to be a complicated one, in the sense that
both oncogenic and tumor suppressive effects were reported in cancers such as …
both oncogenic and tumor suppressive effects were reported in cancers such as …
Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis
L Emdad, SG Lee, ZZ Su, HY Jeon… - Proceedings of the …, 2009 - National Acad Sciences
Astrocyte-elevated gene-1 (AEG-1) expression is increased in multiple cancers and plays a
central role in Ha-ras-mediated oncogenesis through the phosphatidylinositol 3-kinase …
central role in Ha-ras-mediated oncogenesis through the phosphatidylinositol 3-kinase …