Finding a widely available cure for sickle cell anemia (HbSS) still remains a challenge one
hundred years after its discovery as a genetically inherited disease. However, growing …

Sickle cell anemia is a genetically inherited disease in which the “SS” individual possesses
an abnormal beta globin gene. A single base substitution in the gene encoding the human β …

Background Sickle cell disease (SCD) is an inherited blood disorder that predominantly
affects individuals in sub-Saharan Africa. However, research that elucidates links between …

Sickle cell disease is an autosomal recessive disorder of the beta-globin gene, with resultant
deformation of the red blood cells and variable clinical outcomes. Nigeria is recognised as …

Background Mineral bone disorders (MBD) are common in sickle cell anemia (SCA).
Frequent vaso-occlusive crises (VOC) further impact MBD in children with SCA. We …

Nutritional research in sickle cell disease has been the focus in recent times owing to not
only specific nutritional deficiencies, but also the improvements associated with less painful …

Blood biochemistry has significant effect on pathophysiology of human body. Recently few
studies found the association of biochemical abnormalities in sickle cell patients. Sickle cell …

Background and Objectives: Imbalance of calcium/magnesium ratio could lead to clinical
complications in sickle cell disease (SCD). Low levels of magnesium have been associated …

Sickle cell disease (SCD) is a genetically inherited disease in which the “SS” individual
possesses two copies of the abnormal beta-globin gene. This disease is one of the most …

The aim of this study was to measure the body electrolytes (in plasma) such as sodium
(Na+) and potassium (k+) in adult sickle cell patients with genotype (HbSS) genotype and …