Hot spots-making directed evolution easier
Directed evolution has emerged as a powerful strategy to engineer various properties of
proteins. Traditional methods to construct libraries such as error-prone PCR and DNA …
proteins. Traditional methods to construct libraries such as error-prone PCR and DNA …
Protein flexibility in the light of structural alphabets
P Craveur, AP Joseph, J Esque, TJ Narwani… - Frontiers in molecular …, 2015 - frontiersin.org
Protein structures are valuable tools to understand protein function. Nonetheless, proteins
are often considered as rigid macromolecules while their structures exhibit specific flexibility …
are often considered as rigid macromolecules while their structures exhibit specific flexibility …
iHSP-PseRAAAC: Identifying the heat shock protein families using pseudo reduced amino acid alphabet composition
Heat shock proteins (HSPs) are a type of functionally related proteins present in all living
organisms, both prokaryotes and eukaryotes. They play essential roles in protein–protein …
organisms, both prokaryotes and eukaryotes. They play essential roles in protein–protein …
iBLP: An XGBoost‐Based Predictor for Identifying Bioluminescent Proteins
D Zhang, HD Chen, H Zulfiqar, SS Yuan… - … Methods in Medicine, 2021 - Wiley Online Library
Bioluminescent proteins (BLPs) are a class of proteins that widely distributed in many living
organisms with various mechanisms of light emission including bioluminescence and …
organisms with various mechanisms of light emission including bioluminescence and …
Deep-AntiFP: Prediction of antifungal peptides using distanct multi-informative features incorporating with deep neural networks
World widely, Fungal infections have become a serious issue for human beings. Fungal
infections normally happen once invading fungus appear on a specific area of the body and …
infections normally happen once invading fungus appear on a specific area of the body and …
RPI-Pred: predicting ncRNA-protein interaction using sequence and structural information
RNA-protein complexes are essential in mediating important fundamental cellular
processes, such as transport and localization. In particular, ncRNA-protein interactions play …
processes, such as transport and localization. In particular, ncRNA-protein interactions play …
iACP-GAEnsC: Evolutionary genetic algorithm based ensemble classification of anticancer peptides by utilizing hybrid feature space
Cancer is a fatal disease, responsible for one-quarter of all deaths in developed countries.
Traditional anticancer therapies such as, chemotherapy and radiation, are highly expensive …
Traditional anticancer therapies such as, chemotherapy and radiation, are highly expensive …
Biotite: a unifying open source computational biology framework in Python
P Kunzmann, K Hamacher - BMC bioinformatics, 2018 - Springer
Background As molecular biology is creating an increasing amount of sequence and
structure data, the multitude of software to analyze this data is also rising. Most of the …
structure data, the multitude of software to analyze this data is also rising. Most of the …
[HTML][HTML] Extension of the classical classification of β-turns
AG de Brevern - Scientific reports, 2016 - nature.com
The functional properties of a protein primarily depend on its three-dimensional (3D)
structure. These properties have classically been assigned, visualized and analysed on the …
structure. These properties have classically been assigned, visualized and analysed on the …
Predicting protein flexibility through the prediction of local structures
A Bornot, C Etchebest… - … : Structure, Function, and …, 2011 - Wiley Online Library
Protein structures are valuable tools for understanding protein function. However, protein
dynamics is also considered a key element in protein function. Therefore, in addition to …
dynamics is also considered a key element in protein function. Therefore, in addition to …