Mechanisms of microRNA biogenesis and stability control in plants

L Zhang, Y Xiang, S Chen, M Shi, X Jiang… - Frontiers in Plant …, 2022 - frontiersin.org
MicroRNAs (miRNAs), a class of endogenous, non-coding RNAs, which is 20–24 nucleotide
long, regulate the expression of its target genes post-transcriptionally and play critical roles …

Keeping up with the miRNAs: current paradigms of the biogenesis pathway

R Mencia, L Gonzalo, I Tossolini… - Journal of …, 2023 - academic.oup.com
For many years we have studied the processes involved in producing miRNAs in plants and
the numerous differences from their metazoan counterpart. A well-defined catalytic process …

R-loops at microRNA encoding loci promote co-transcriptional processing of pri-miRNAs in plants

L Gonzalo, I Tossolini, T Gulanicz, DA Cambiagno… - Nature Plants, 2022 - nature.com
In most organisms, the maturation of nascent RNAs is coupled to transcription. Unlike in
animals, the RNA polymerase II (RNAPII) transcribes microRNA genes (MIRNA s) as long …

HASTY modulates miRNA biogenesis by linking pri-miRNA transcription and processing

DA Cambiagno, AJ Giudicatti, AL Arce, D Gagliardi… - Molecular plant, 2021 - cell.com
Post-transcriptional gene silencing mediated by microRNAs (miRNAs) modulates numerous
developmental and stress response pathways. For the last two decades, HASTY (HST), the …

Recent insights into plant miRNA biogenesis: multiple layers of miRNA level regulation

M Bajczyk, A Jarmolowski, M Jozwiak, A Pacak… - Plants, 2023 - mdpi.com
MicroRNAs are small RNAs, 20–22 nt long, the main role of which is to downregulate gene
expression at the level of mRNAs. MiRNAs are fundamental regulators of plant growth and …

Cotranscriptional RNA processing and modification in plants

S Marquardt, E Petrillo, PA Manavella - The Plant Cell, 2023 - academic.oup.com
The activities of RNA polymerases shape the epigenetic landscape of genomes with
profound consequences for genome integrity and gene expression. A fundamental event …

Arabidopsis RBV is a conserved WD40 repeat protein that promotes microRNA biogenesis and ARGONAUTE1 loading

C Liang, Q Cai, F Wang, S Li, C You, C Xu… - Nature …, 2022 - nature.com
MicroRNAs (miRNAs) play crucial roles in gene expression regulation through RNA
cleavage or translation repression. Here, we report the identification of an evolutionarily …

Domain organization, expression, subcellular localization, and biological roles of ARGONAUTE proteins in Arabidopsis

A Martín-Merchán, B Moro, A Bouet… - Journal of …, 2023 - academic.oup.com
ARGONAUTE (AGO) proteins are the final effectors of small RNA-mediated transcriptional
and post-transcriptional silencing pathways. Plant AGO proteins are essential for preserving …

MicroRNAs: emerging regulators in horticultural crops

M He, X Kong, Y Jiang, H Qu, H Zhu - Trends in Plant Science, 2022 - cell.com
Horticulture is one of the oldest agricultural practices with great popularity throughout the
world. Horticultural crops include fruits, vegetables, ornamental plants, as well as medicinal …

Cytoplasmic HYL1 modulates miRNA-mediated translational repression

X Yang, W Dong, W Ren, Q Zhao, F Wu, Y He - The Plant Cell, 2021 - academic.oup.com
MicroRNAs (miRNAs) control various biological processes by repressing target mRNAs. In
plants, miRNAs mediate target gene repression via both mRNA cleavage and translational …