Long-term biobehavioral effects of maternal separation in the rat: consistent or confusing?
J Lehmann, J Feldon - Reviews in the Neurosciences, 2000 - degruyter.com
Over the last decades of research there has been increasing interest in endocrine and
behavioral effects of postnatal environmental manipulations. A manipulation procedure that …
behavioral effects of postnatal environmental manipulations. A manipulation procedure that …
Methylmercury developmental neurotoxicity: a comparison of effects in humans and animals
TM Burbacher, PM Rodier, B Weiss - Neurotoxicology and teratology, 1990 - Elsevier
A qualitative and quantitative comparison of the neuropathological and neurobehavioral
effects of early methylmercury (MeHg) exposure is presented. The focus of the qualitative …
effects of early methylmercury (MeHg) exposure is presented. The focus of the qualitative …
Principles and pitfalls in the analysis of prenatal treatment effects in multiparous species
RR Holson, B Pearce - Neurotoxicology and teratology, 1992 - Elsevier
Developmental studies often assess the effect of treatment of the pregnant mother on
offspring. The use of multiparous species such as rats and mice in such studies creates a …
offspring. The use of multiparous species such as rats and mice in such studies creates a …
[HTML][HTML] An analysis of the limitations and uncertainties of in vivo developmental neurotoxicity testing and assessment to identify the potential for alternative …
M Paparella, SH Bennekou, A Bal-Price - Reproductive Toxicology, 2020 - Elsevier
Limitations of regulatory in vivo developmental neurotoxicity (DNT) testing and assessment
are well known, such as the 3Rs conflict, low throughput, high costs, high specific expertise …
are well known, such as the 3Rs conflict, low throughput, high costs, high specific expertise …
[图书][B] Developmental and reproductive toxicology: a practical approach
RD Hood, RD Hood - 2005 - taylorfrancis.com
Completely revised and updated, Developmental and Reproductive Toxicology: A Practical
Approach, Second Edition draws together valuable information typically scattered …
Approach, Second Edition draws together valuable information typically scattered …
A retrospective performance assessment of the developmental neurotoxicity study in support of OECD test guideline 426
SL Makris, K Raffaele, S Allen… - Environmental …, 2009 - ehp.niehs.nih.gov
Objective We conducted a review of the history and performance of developmental
neurotoxicity (DNT) testing in support of the finalization and implementation of Organisation …
neurotoxicity (DNT) testing in support of the finalization and implementation of Organisation …
Neurobehavioral effects of developmental methylmercury exposure.
SG Gilbert, KS Grant-Webster - Environmental health …, 1995 - ehp.niehs.nih.gov
Methylmercury (MeHg) is a global environmental problem and is listed by the International
Program of Chemical Safety as one of the six most dangerous chemicals in the world's …
Program of Chemical Safety as one of the six most dangerous chemicals in the world's …
[HTML][HTML] A perspective on In vitro developmental neurotoxicity test assay results: An expert panel review
DR Juberg, DA Fox, PA Forcelli, S Kacew… - Regulatory Toxicology …, 2023 - Elsevier
For decades, there has been increasing concern about the potential developmental
neurotoxicity (DNT) associated with chemicals. Regulatory agencies have historically …
neurotoxicity (DNT) associated with chemicals. Regulatory agencies have historically …
Thyroxine replacement attenuates hypothyroxinemia, hearing loss, and motor deficits following developmental exposure to Aroclor 1254 in rats
ES Goldey, KM Crofton - Toxicological Sciences, 1998 - Elsevier
The nervous system is dependent upon thyroid hormones for normal development, and we
previously reported that developmental Aroclor 1254 (A1254) exposure caused …
previously reported that developmental Aroclor 1254 (A1254) exposure caused …
Developmental toxicity of diesel exhaust: a review of studies in experimental animals
M Ema, M Naya, M Horimoto, H Kato - Reproductive toxicology, 2013 - Elsevier
Diesel exhaust (DE) is a complex mixture of combustion products of diesel fuel, including
gases and diesel exhaust particles (DEPs), commonly known as soot, that contains many …
gases and diesel exhaust particles (DEPs), commonly known as soot, that contains many …