Biflavonoids: Important Contributions to the Health Benefits of Ginkgo (Ginkgo biloba L.)

D Šamec, E Karalija, S Dahija, STS Hassan - Plants, 2022 - mdpi.com
Ginkgo (Ginkgo biloba L.) is one of the most distinctive plants, characterized by excellent
resistance to various environmental conditions. It is used as an ornamental plant and is …

Targeting Ras-ERK cascade by bioactive natural products for potential treatment of cancer: an updated overview

ES Ali, S Akter, S Ramproshad, B Mondal… - Cancer cell …, 2022 - Springer
MAPK (mitogen-activated protein kinase) or ERK (extracellular-signal-regulated kinase)
pathway is an important link in the transition from extracellular signals to intracellular …

Pharmacological effects and therapeutic potential of natural compounds in neuropsychiatric disorders: An update

P Asgharian, C Quispe, J Herrera-Bravo… - Frontiers in …, 2022 - frontiersin.org
Neuropsychiatric diseases are a group of disorders that cause significant morbidity and
disability. The symptoms of psychiatric disorders include anxiety, depression, eating …

Colloidal aggregation confounds cell-based Covid-19 antiviral screens

IS Glenn, LN Hall, MM Khalid, M Ott… - Journal of Medicinal …, 2024 - ACS Publications
Colloidal aggregation is one of the largest contributors to false positives in early drug
discovery. Here, we consider aggregation's role in cell-based infectivity assays in Covid-19 …

Computational Approaches for Structure-Based Molecular Characterization and Functional Annotation of the Fusion Protein of Nipah henipavirus

ASM Saikat, RC Das, MC Das - Chemistry Proceedings, 2022 - mdpi.com
Throughout history, viral epidemics of varying frequency and intensity have been
responsible for inducing panic and causing widespread damage. The Nipah virus has one …

Activities and molecular mechanisms of diterpenes, diterpenoids, and their derivatives in rheumatoid arthritis

M Torequl Islam, C Quispe… - Evidence‐Based …, 2022 - Wiley Online Library
Diterpenes and their derivatives have many biological activities, including anti‐inflammatory
and immunomodulatory effects. To date, several diterpenes, diterpenoids, and their …

A comprehensive review on traditional uses, phytochemistry and pharmacological properties of Paeoniaemodi Wall. ex Royle: current landscape and future …

N Zahra, J Iqbal, M Arif, BA Abbasi, H Sher, AF Nawaz… - Chinese Medicine, 2023 - Springer
Abstract Paeonia emodi Wall. ex Royle is commonly known as Himalayan paeony has great
importance as a food and medicine. The practice of Paeonia emodi Wall. ex Royle is very …

Design of a multi-epitope vaccine against SARS-CoV-2: immunoinformatic and computational methods

MO Rafi, K Al-Khafaji, MT Sarker, T Taskin-Tok… - RSC …, 2022 - pubs.rsc.org
A novel infectious agent, SARS-CoV-2, is responsible for causing the severe respiratory
disease COVID-19 and death in humans. Spike glycoprotein plays a key role in viral …

Thermodynamic and kinetic studies on antioxidant capacity of amentoflavone: a DFT (density functional theory) computational approach

PT Thuy, NT Son - Free Radical Research, 2022 - Taylor & Francis
Density functional theory (DFT) at the theoretical M06-2X/6-311G (d, p) level was used to
assess thermodynamics and kinetics in the antioxidative action of amentoflavone (AF). The …

A detailed understanding of the COL10A1 and SOX9 genes interaction based on potentially damaging mutations in gastric cancer using computational techniques

SH Aktas, T Taskin-Tok, K Al-Khafaji… - Journal of Biomolecular …, 2022 - Taylor & Francis
Gastric cancer (GC) has limited effective treatment options and is followed up with
biomarkers that have insufficient sensitivity and specificity. Recent studies on Collagen Type …