[HTML][HTML] Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial
Selective serotonin reuptake inhibitors (SSRIs) are widely used for treating neuropsychiatric
disorders. However, the exact mechanism of action and why effects can take several weeks …
disorders. However, the exact mechanism of action and why effects can take several weeks …
Cognitive changes in patients with unipolar TRD treated with IV ketamine: A systematic review
V Grasso, G Gutierrez, N Alzbeidi… - Progress in Neuro …, 2024 - Elsevier
Background Unipolar treatment-resistant depression (MDD-TRD) is associated with
neurocognitive impairment. Ketamine, an emerging treatment for MDD-TRD, may have …
neurocognitive impairment. Ketamine, an emerging treatment for MDD-TRD, may have …
Change in Cognitive Function over the Course of Major Depressive Disorder: A Systematic Review and Meta-analysis
E Ahern, J White, E Slattery - Neuropsychology Review, 2024 - Springer
Major depressive disorder (MDD) is associated with significant cognitive deficits during the
acute and remitted stages. The aim of this systematic review and meta-analysis was to …
acute and remitted stages. The aim of this systematic review and meta-analysis was to …
[HTML][HTML] 5-HT4 receptor agonist effects on functional connectivity in the human brain: Implications for procognitive action
Background Cognitive deficits are often comorbid with mood disorders and can cause
significant functional impairment even after resolution of the primary mood symptoms. We do …
significant functional impairment even after resolution of the primary mood symptoms. We do …
[HTML][HTML] Deep phenotyping towards precision psychiatry of first-episode depression—the Brain Drugs-Depression cohort
Abstract Background Major Depressive Disorder (MDD) is a heterogenous brain disorder,
with potentially multiple psychosocial and biological disease mechanisms. This is also a …
with potentially multiple psychosocial and biological disease mechanisms. This is also a …
Adipocytokines levels as potential biomarkers for discriminating patients with a diagnosis of depressive disorder from healthy controls
E Małujło-Balcerska, T Pietras - Journal of psychiatric research, 2024 - Elsevier
Background Depressive disorder is a complex mental health condition in which the
etiopathogenesis involves several factors. Suitable biomarkers for the development of …
etiopathogenesis involves several factors. Suitable biomarkers for the development of …
Stress hormone dynamics are coupled to brain serotonin 4 receptor availability in unmedicated patients with major depressive disorder: a neuropharm study
GM Vulpius, K Köhler-Forsberg… - International Journal …, 2023 - academic.oup.com
Background A prominent finding in major depressive disorder (MDD) is distorted stress
hormone dynamics, which is regulated by serotonergic brain signaling. An interesting …
hormone dynamics, which is regulated by serotonergic brain signaling. An interesting …
Serotonin and emotion regulation: the impact of tryptophan depletion on emotional experience, neural and autonomic activity
MI Bîlc, A Iacob, RD Szekely-Copîndean, B Kiss… - Cognitive, Affective, & …, 2023 - Springer
The involvement of serotonin in emotion and psychopathology has been extensively
examined. Studies using acute tryptophan depletion (ATD) have found limited effects on …
examined. Studies using acute tryptophan depletion (ATD) have found limited effects on …
[HTML][HTML] Cognitive decline and its associated factors in patients with major depressive disorder
HZ Ab Latiff, S Ariaratnam, N Shuib, MR Isa - Healthcare, 2023 - mdpi.com
Background: Major Depressive Disorder (MDD) is a significant and common mental health
problem occurring worldwide. Cognitive decline is frequently observed during acute and …
problem occurring worldwide. Cognitive decline is frequently observed during acute and …
[HTML][HTML] No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state
Background Methylation of serotonin-related genes has been proposed as a plausible gene-
by-environment link which may mediate environmental stress, depressive and anxiety …
by-environment link which may mediate environmental stress, depressive and anxiety …