Genetics of fat tissue accumulation in pigs: a comparative approach

M Switonski, M Stachowiak, J Cieslak, M Bartz… - Journal of Applied …, 2010 - Springer
Fatness traits are important in pig production since they influence meat quality and fattening
efficiency. On the other hand, excessive fat accumulation in humans has become a serious …

Diversity across major and candidate genes in European local pig breeds

M Muñoz, R Bozzi, F García, Y Núñez, C Geraci… - PloS one, 2018 - journals.plos.org
The aim of this work was to analyse the distribution of causal and candidate mutations
associated to relevant productive traits in twenty local European pig breeds. Also, the …

Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat

A Puig-Oliveras, M Revilla, A Castelló, AI Fernández… - Scientific reports, 2016 - nature.com
The aim of this work is to better understand the genetic mechanisms determining two
complex traits affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid …

Disruption of the ZBED6 binding site in intron 3 of IGF2 by CRISPR/Cas9 leads to enhanced muscle development in Liang Guang Small Spotted pigs

X Liu, H Liu, M Wang, R Li, J Zeng, D Mo, P Cong… - Transgenic …, 2019 - Springer
Insulin-like growth factor 2 (IGF2) plays an important role in the development of the foetus
and in post-natal growth and development. A SNP within intron 3 of porcine IGF2 disrupts a …

QTL for microstructural and biophysical muscle properties and body composition in pigs

K Wimmers, I Fiedler, T Hardge, E Murani… - BMC genetics, 2006 - Springer
Background The proportion of muscle fibre types and their size affect muscularity as well as
functional properties of the musculature and meat quality. We aimed to identify QTL for …

Analysis of porcine IGF2 gene expression in adipose tissue and its effect on fatty acid composition

L Criado-Mesas, M Ballester, D Crespo-Piazuelo… - PLoS …, 2019 - journals.plos.org
IGF2: g. 3072G> A polymorphism has been described as the causal mutation of a maternally
imprinted QTL for muscle growth and fat deposition in pigs. The objective of the current work …

The insulin-like growth factor 2 (IGF2) gene intron3-g.3072G>A polymorphism is not the only Sus scrofa chromosome 2p mutation affecting meat production and carcass traits in …

L Fontanesi, C Speroni, L Buttazzoni… - Journal of animal …, 2010 - academic.oup.com
The objective of this study was to evaluate the effects of mutations in 2 genes [IGF2 and
cathepsin D (CTSD)] that map on the telomeric end of the p arm of SSC2. In this region, an …

Combined line-cross and half-sib QTL analysis in Duroc–Pietrain population

G Liu, JJ Kim, E Jonas, K Wimmers, S Ponsuksili… - Mammalian …, 2008 - Springer
A Duroc–Pietrain resource population was built to detect quantitative trait loci (QTL) that
affect growth, carcass composition, and pork quality. The data were analyzed by applying …

[HTML][HTML] Genomic architecture of carcass and pork traits and their association with immune capacity

T Jové-Juncà, D Crespo-Piazuelo… - animal, 2024 - Elsevier
Carcass and pork traits have traditionally been considered of prime importance in pig
breeding programmes. However, the changing conditions in modern farming, coupled with …

A domesticated transposon mediates the effects of a single‐nucleotide polymorphism responsible for enhanced muscle growth

F Butter, D Kappei, F Buchholz, M Vermeulen… - EMBO …, 2010 - embopress.org
Single‐nucleotide polymorphisms (SNPs) in the regulatory regions of the genome can have
a profound impact on phenotype. The G3072A polymorphism in intron 3 of insulin‐like …