[HTML][HTML] Considerations for polymers used in ocular drug delivery
MM Allyn, RH Luo, EB Hellwarth… - Frontiers in …, 2022 - frontiersin.org
Purpose Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …
been seen in the most common causes including glaucoma, age-related macular …
Clinical pharmacology of intravitreal anti-VEGF drugs
Clinical efficacy of intravitreal anti-VEGF drugs has been widely demonstrated in several
angiogenesis-driven eye diseases including diabetic macular edema and the neovascular …
angiogenesis-driven eye diseases including diabetic macular edema and the neovascular …
[HTML][HTML] Exosomes derived from mesenchymal stem cells modulate miR-126 to ameliorate hyperglycemia-induced retinal inflammation via targeting HMGB1
W Zhang, Y Wang, Y Kong - Investigative ophthalmology & …, 2019 - iovs.arvojournals.org
Purpose: In this study, we aim to investigate whether mesenchymal stem cell (MSC)-derived
exosomes (MSC-Exos) could regulate hyperglycemia-induced retinal inflammation by …
exosomes (MSC-Exos) could regulate hyperglycemia-induced retinal inflammation by …
[HTML][HTML] The role of inflammation in immune system of diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications
T Yue, Y Shi, S Luo, J Weng, Y Wu… - Frontiers in …, 2022 - frontiersin.org
Diabetic retinopathy is one of the most common complications of diabetes mellitus and the
leading cause of low vision and blindness worldwide. Mounting evidence demonstrates that …
leading cause of low vision and blindness worldwide. Mounting evidence demonstrates that …
Retinal vascular cystoid macular edema: review and new theory
RF Spaide - Retina, 2016 - journals.lww.com
Retinal vascular disease has the potential to affect hundreds of millions of people, with the
inherent risk of vision loss related to cystoid macular edema. Although there have been …
inherent risk of vision loss related to cystoid macular edema. Although there have been …
How to prevent the microvascular complications of type 2 diabetes beyond glucose control
WM Valencia, H Florez - Bmj, 2017 - bmj.com
Microvascular complications (retinopathy, nephropathy, and neuropathy) affect hundreds of
millions of patients with type 2 diabetes. They usually affect people with longstanding or …
millions of patients with type 2 diabetes. They usually affect people with longstanding or …
Biological drug therapy for ocular angiogenesis: Anti‐VEGF agents and novel strategies based on nanotechnology
ML Formica, HG Awde Alfonso… - Pharmacology Research …, 2021 - Wiley Online Library
Currently, biological drug therapy for ocular angiogenesis treatment is based on the
administration of anti‐VEGF agents via intravitreal route. The molecules approved with this …
administration of anti‐VEGF agents via intravitreal route. The molecules approved with this …
[HTML][HTML] Visualization of changes in the foveal avascular zone in both observed and treated diabetic macular edema using optical coherence tomography angiography
Background Central vision loss in diabetic retinopathy is commonly related to diabetic
macular edema (DME). The objective of this study was to describe changes between …
macular edema (DME). The objective of this study was to describe changes between …
Recent perspectives on the delivery of biologics to back of the eye
Introduction: Biologics are generally macromolecules, large in size with poor stability in
biological environments. Delivery of biologics to tissues at the back of the eye remains a …
biological environments. Delivery of biologics to tissues at the back of the eye remains a …
Single-cell and bulk transcriptomics reveals M2d macrophages as a potential therapeutic strategy for mucosal healing in ulcerative colitis
W Lai, C Xian, M Chen, D Luo, J Zheng, S Zhao… - International …, 2023 - Elsevier
Mucosal healing is essential for treating ulcerative colitis (UC), which results from
imbalanced macrophage polarization and dysregulated inflammatory responses. However …
imbalanced macrophage polarization and dysregulated inflammatory responses. However …