MicroRNAs (miRNAs) are short non-coding RNAs with a length of∼ 22 nucleotides,
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …

Toxic metals are extensively found in the environment, households, and workplaces and
contaminate food and drinking water. The crosstalk between environmental exposure to …

Tumor-derived cell lines have served as vital models to advance our understanding of
oncogene function and therapeutic responses. Although substantial effort has been made to …

Objectives MicroRNAs (miRNAs) are a type of small noncoding RNA employed by the cells
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …

Three-dimensional (3D) cell culture is gaining acceptance in response to the need for
cellular models that better mimic physiologic tissues. Spheroids are one such 3D model …

The advent of techniques such as microarrays and high-throughput sequencing has
revolutionized our ability to examine messenger RNA (mRNA) expression within the …

MicroRNAs (miRNAs) are endogenous, time sequencing, conserved and small non-coding
RNA molecules (19-25 bp long) that regulate gene expression at the post-transcriptional …

There is increasing evidence that the expression of microRNA (miRNA) in cancer is
associated with chemosensitivity but the mechanism of miRNA-induced chemoresistance …

Cell signaling is dominated by analyzing positive responses to stimuli. Signal activation is
balanced by negative regulators that are generally considered to terminate signaling. Rather …

The study of a class of small non-coding RNA molecules, named microRNAs (miRNAs), has
advanced our understanding of many of the fundamental processes of cancer biology and …