In the last century, natural compounds have achieved remarkable achievements in the
treatment of tumors through chemotherapy. This inspired scientists to continuously explore …

MMP-2 and MMP-9 genes have been suggested to play a role in breast cancer. Their
functions have been associated with invasion and metastasis of breast cancer; however …

We conducted this study to explore the association between matrix metalloproteinase (MMP)
gene polymorphisms and breast cancer (BC) risk in the Caucasian women of Russia. In …

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases, which
play critical roles in cancer progression and metastasis. In recent years, many researchers …

Genetic and epigenetic modifications of genes involved in the key regulatory pathways play
a significant role in the pathophysiology and progression of multifactorial diseases. The …

Abstract Matrix metalloproteinase‑1 (MMP1) participates in the metastasis of pancreatic
cancer, and its expression can be regulated by endogenous microRNAs (miRs/miRNAs) …

Matrix metallopeptidase 3 or MMP3, is a zinc-dependent proteolytic enzyme that is involved
in various physiological processes via modification of the extracellular matrix. In particular …

Introduction Breast cancer metastasis is the main cause of cancer-related death in women
worldwide. Current therapies have remarkably improved the prognosis of breast cancer …

The tumor microenvironment (TME) consists of numerous biologically relevant elements.
One of the most important components of the TME is the extracellular matrix (ECM). The …

Colon cancer (CC) is a prevalent malignant tumor of the gastrointestinal tract and ranks
among the leading causes of death in cancer patients worldwide. Cucurbitacin, a group of …