Bio‐based production of C2–C6 platform chemicals

YS Jang, B Kim, JH Shin, YJ Choi… - Biotechnology and …, 2012 - Wiley Online Library
Platform chemicals composed of 2–6 carbons derived from fossil resources are used as
important precursors for making a variety of chemicals and materials, including solvents …

Recent advances in biological production of 3-hydroxypropionic acid

V Kumar, S Ashok, S Park - Biotechnology advances, 2013 - Elsevier
Hydroxypropionic acid (3-HP) is a valuable platform chemical that can be produced
biologically from glucose or glycerol. This review article provides an overview and the …

Recent advances in biological production of 1, 3-propanediol: new routes and engineering strategies

F Zhu, D Liu, Z Chen - Green Chemistry, 2022 - pubs.rsc.org
1, 3-Propanediol (1, 3-PDO) is an important chemical which has been widely used in the
cosmetics, pharmaceutical, and especially polymer industries. The production of 1, 3-PDO …

Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source

V Kumar, S Park - Biotechnology advances, 2018 - Elsevier
Klebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol
efficiently under both aerobic and anaerobic conditions. This microbe is considered an …

High Production of 3-Hydroxypropionic Acid in Klebsiella pneumoniae by Systematic Optimization of Glycerol Metabolism

Y Li, X Wang, X Ge, P Tian - Scientific reports, 2016 - nature.com
Hydroxypropionic acid (3-HP) is an important platform chemical proposed by the United
States Department of Energy. 3-HP can be converted to a series of bulk chemicals …

Biosynthesis of diverse α, ω-diol-derived polyhydroxyalkanoates by engineered Halomonas bluephagenesis

X Yan, X Liu, LP Yu, F Wu, XR Jiang, GQ Chen - Metabolic Engineering, 2022 - Elsevier
Polyhydroxyalkanoates (PHA) are a family of biodegradable and biocompatible plastics with
potential to replace petroleum based plastics. Diversity of PHA monomer structures provides …

Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks

Y Chen, J Nielsen - Current opinion in biotechnology, 2013 - Elsevier
Highlights•Microbial production of chemicals is an attractive alternative to chemical
synthesis.•An integrated approach would be required to construct robust microbial chemical …

Anaerobic fermentation for production of carboxylic acids as bulk chemicals from renewable biomass

J Wang, M Lin, M Xu, ST Yang - Anaerobes in biotechnology, 2016 - Springer
Biomass represents an abundant carbon-neutral renewable resource which can be
converted to bulk chemicals to replace petrochemicals. Carboxylic acids have wide …

The effect of crude glycerol impurities on 1, 3-propanediol biosynthesis by Klebsiella pneumoniae DSMZ 2026

M Laura, T Monica, V Dan-Cristian - Renewable Energy, 2020 - Elsevier
This study aimed to evaluate the ability of Klebsiella pneumoniae DSMZ 2026 to
biosynthesize 1, 3-propanediol (1, 3-PD) during batch fermentations when pure glycerol was …

Biological production of 3-hydroxypropionic acid: an update on the current status

L Matsakas, K Hrůzová, U Rova, P Christakopoulos - Fermentation, 2018 - mdpi.com
The production of high added-value chemicals from renewable resources is a necessity in
our attempts to switch to a more sustainable society. 3-Hydroxypropionic acid (3HP) is a …