Candida albicans and candidalysin in inflammatory disorders and cancer

J Ho, G Camilli, JS Griffiths, JP Richardson… - …, 2021 - Wiley Online Library
As our understanding of mycology progresses, the impact of fungal microbes on human
health has become increasingly evident. Candida albicans is a common commensal fungus …

Molecular mechanisms leading from periodontal disease to cancer

BK Sobocki, CA Basset, B Bruhn-Olszewska… - International Journal of …, 2022 - mdpi.com
Periodontitis is prevalent in half of the adult population and raises critical health concerns as
it has been recently associated with an increased risk of cancer. While information about the …

Antifungal drug repurposing

JH Kim, LW Cheng, KL Chan, CC Tam, N Mahoney… - Antibiotics, 2020 - mdpi.com
Control of fungal pathogens is increasingly problematic due to the limited number of
effective drugs available for antifungal therapy. Conventional antifungal drugs could also …

Novel avenues for identification of new antifungal drugs and current challenges

J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Some of the fungi have become pathogenic to humans, and these opportunistic
pathogens are able to cause severe systemic mycoses. Areas covered The number of …

NADPH-cytochrome P450 reductase Ccr1 is a target of tamoxifen and participates in its antifungal activity via regulating cell wall integrity in fission yeast

Q Liu, X Guo, G Jiang, G Wu, H Miao… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Invasive fungal diseases are a leading cause of mortality among immunocompromised
populations. Treatment is notoriously difficult due to the limited number of antifungal drugs …

Alterations of fungal microbiota in patients with cholecystectomy

J Xu, X Ren, Y Liu, Y Zhang, Y Zhang, G Chen… - Frontiers in …, 2022 - frontiersin.org
Increasing evidence suggests a high risk of gastrointestinal postoperative comorbidities
(such as colorectal cancer) in patients with postcholecystectomy (PC). Although previous …

[HTML][HTML] Candidiasis in breast cancer: Tumor progression or not?

S Ashrafi, AA Amini, P Karimi… - Iranian Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Candida albicans is an “opportunistic fungal agent” in cancer patients that can become
colonized in both mucosal and deep tissues and cause severe infections. Most evidence …

Inhibition of azole-resistant Candida albicans ATPase and oxidoreductase activity by a flavonoid from Dalea elegans

P Passero, M Muthular, S Barceló, V Miozza… - Journal of Medical …, 2022 - Elsevier
Abstract Background. The flavonoid 2′, 4′-dihydroxy-5′-(1′′′, 1′′′-dimethylallyl)-
8-prenylpinocembrin (8PP) obtained from Dalea elegans roots inhibits cell growth and cdr …

Tamoxifen: from anti-cancer to antifungal drug

AAHS AL-Janabi, HAS Al-Mosawe… - International Journal of …, 2019 - ijmedrev.com
Tamoxifen (TAM) is an important drug for treatment of breast cancer. It is most effective
against estrogen receptor-positive and negative breast cancer. Protective adjuvant is …

[PDF][PDF] Effect of cancer treatment on the worsening of periodontal disease and dental caries: A preliminary, retrospective study

S Soutome, M Otsuru, Y Kawashita… - Oral Health Prev …, 2021 - quintpub.com
Purpose: To investigate the effect of cancer treatment on the worsening of dental caries and
periodontal disease. Materials and Methods: Fifty-three adult cancer patients who …