Eukaryotic protein synthesis is the highly conserved, complex mechanism of translating
genetic information into proteins. Although this process is essential for cellular …

Covering: 1949 to 2011 This review highlights the broad range of science that has arisen
from the isolation of pederin, the mycalamides, theopederins, and onnamides, and …

Translation of CGA codon repeats in the yeast Saccharomyces cerevisiae is inefficient,
resulting in dose-dependent reduction in expression and in production of an mRNA …

Metastasis remains a leading cause of cancer mortality due to the lack of specific inhibitors
against this complex process. To identify compounds selectively targeting the metastatic …

All organisms have evolved a wide range of strategies to protect against natural enemies,
from complex avoidance behaviours to sophisticated immune systems, and insects are no …

Electrophilic groups, such as Michael acceptors, expoxides, are common motifs in natural
products (NPs). Electrophilic NPs can act through covalent modification of cysteinyl thiols on …

Covering: 2000 to 2020 The translation of mRNA into proteins is a precisely regulated,
complex process that can be divided into three main stages, ie initiation, elongation …

Protein synthesis plays an essential role in cell proliferation, differentiation, and survival.
Inhibitors of eukaryotic translation have entered the clinic, establishing the translation …

Covering: 1951 to 2022 Packed with nutrients and unable to escape, eggs are the most
vulnerable stage of an animal's life cycle. Consequently, many species have evolved …

The central dogma of molecular biology, that DNA is transcribed into RNA and RNA
translated into protein, was coined in the early days of modern biology. Back in the 1950s …