Adiponectin is an adipocyte-specific factor, first described in 1995. Over the past two
decades, numerous studies have elucidated the physiological functions of adiponectin in …

Adiponectin is one of the most important adipocytokines secreted by adipocytes and is
called a “guardian angel adipocytokine” owing to its unique biological functions. Adiponectin …

Summary Fibroblast growth factor 21 (FGF21) is a metabolic hormone with pleiotropic effects
on regulating glucose and lipid homeostasis and insulin sensitivity. However, the …

Obesity is characterized by increased storage of fatty acids in an expanded adipose tissue
mass and is closely associated with the development of insulin resistance in peripheral …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

Obesity has become a universal and major public health problem with increasing
prevalence in both adults and children in the 21st century, even in developing countries …

Obesity is associated with an array of health problems in adult and pediatric populations.
Understanding the pathogenesis of obesity and its metabolic sequelae has advanced …

Context Adipose tissue is increasingly recognized as an active endocrine organ with many
secretory products and part of the innate immune system. With obesity, macrophages …

The endocrine functions of the adipose organ are widely studied at this stage. The adipose
organ, and in particular adipocytes, communicate with almost all other organs. Although …