Hallmarks of environmental insults

A Peters, TS Nawrot, AA Baccarelli - Cell, 2021 - cell.com
Environmental insults impair human health around the world. Contaminated air, water, soil,
food, and occupational and household settings expose humans of all ages to a plethora of …

The involvement of the oxidative stress status in cancer pathology: a double view on the role of the antioxidants

KF Zahra, R Lefter, A Ali, EC Abdellah… - Oxidative Medicine …, 2021 - Wiley Online Library
Oxygen‐free radicals, reactive oxygen species (ROS) or reactive nitrogen species (RNS),
are known by their “double‐sided” nature in biological systems. The beneficial effects of …

The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013

JA Vizcaíno, RG Côté, A Csordas… - Nucleic acids …, 2012 - academic.oup.com
Abstract The PRoteomics IDEntifications (PRIDE, http://www. ebi. ac. uk/pride) database at
the European Bioinformatics Institute is one of the most prominent data repositories of mass …

[HTML][HTML] Proteostasis, oxidative stress and aging

I Korovila, M Hugo, JP Castro, D Weber, A Höhn… - Redox biology, 2017 - Elsevier
The production of reactive species is an inevitable by-product of metabolism and thus, life
itself. Since reactive species are able to damage cellular structures, especially proteins, as …

Radical-free biology of oxidative stress

DP Jones - American Journal of Physiology-Cell …, 2008 - journals.physiology.org
Free radical-induced macromolecular damage has been studied extensively as a
mechanism of oxidative stress, but large-scale intervention trials with free radical …

Oxidation resistance of the sulfur amino acids: methionine and cysteine

P Bin, R Huang, X Zhou - BioMed research international, 2017 - Wiley Online Library
Sulfur amino acids are a kind of amino acids which contain sulfhydryl, and they play a
crucial role in protein structure, metabolism, immunity, and oxidation. Our review …

Life and death: metabolic rate, membrane composition, and life span of animals

AJ Hulbert, R Pamplona, R Buffenstein… - Physiological …, 2007 - journals.physiology.org
Maximum life span differences among animal species exceed life span variation achieved
by experimental manipulation by orders of magnitude. The differences in the characteristic …

Trends in oxidative aging theories

FL Muller, MS Lustgarten, Y Jang, A Richardson… - Free Radical Biology …, 2007 - Elsevier
The early observations on the rate-of-living theory by Max Rubner and the report by
Gershman that oxygen free radicals exist in vivo culminated in the seminal proposal in the …

[HTML][HTML] Protein synthesis and quality control in aging

AS Anisimova, AI Alexandrov, NE Makarova… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
Aging is characterized by the accumulation of damage and other deleterious changes,
leading to the loss of functionality and fitness. Age-related changes occur at most levels of …

Oxidative stress and neurotoxicity

LM Sayre, G Perry, MA Smith - Chemical research in toxicology, 2008 - ACS Publications
There is increasing awareness of the ubiquitous role of oxidative stress in
neurodegenerative disease states. A continuing challenge is to be able to distinguish …