The anti-inflammatory and immunomodulatory activities of natural products to control autoimmune inflammation

KD Moudgil, SH Venkatesha - International journal of molecular sciences, 2022 - mdpi.com
Inflammation is an integral part of autoimmune diseases, which are caused by dysregulation
of the immune system. This dysregulation involves an imbalance between pro-inflammatory …

An update on pharmacological potential of boswellic acids against chronic diseases

NK Roy, D Parama, K Banik, D Bordoloi… - International journal of …, 2019 - mdpi.com
Natural compounds, in recent years, have attracted significant attention for their use in the
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …

The journey of boswellic acids from synthesis to pharmacological activities

EA Ragab, MF Abd El-Wahab, AS Doghish… - Naunyn-schmiedeberg's …, 2024 - Springer
There has been a lot of interest in using naturally occurring substances to treat a wide
variety of chronic disorders in recent years. From the gum resin of Boswellia serrata and …

Boswellic acids and their role in chronic inflammatory diseases

HPT Ammon - Anti-inflammatory Nutraceuticals and Chronic Diseases, 2016 - Springer
Boswellic acids, which are pentacyclic triterpenes belong to the active pharmacological
compounds of the oleogum resin of different Boswellia species. In the resin, more than 12 …

[HTML][HTML] Phytochemistry and potential therapeutic actions of Boswellic acids: A mini-review

F Iram, SA Khan, A Husain - Asian Pacific journal of tropical biomedicine, 2017 - Elsevier
The pentacyclic triterpenic acids isolated from the oleo gum resin of various Boswellia
species are collectively called as Boswellic acids (BA). The oleo gum resin obtained from …

[HTML][HTML] Anti-diabetic potential of β-boswellic acid and 11-keto-β-boswellic acid: Mechanistic insights from computational and biochemical approaches

A Khan, I Khan, SA Halim, NU Rehman, N Karim… - Biomedicine & …, 2022 - Elsevier
Abstract β-Boswellic acid (β-BA) and 11-keto-β-boswellic acid (β-KBA) are crucial bioactive
compounds, mostly isolated from frankincense. These compounds are known for their potent …

Mechanistic approach of anti-diabetic compounds identified from natural sources

R Dabur, B Sharma, A Mittal - Chemical Biology Letters, 2018 - pubs.iscience.in
Abstract Type-2 diabetes mellitus (T2DM) is a global disease, which leads to various other
life threatening diseases and affects the quality of life. Current therapies of T2DM have …

[HTML][HTML] Boswellic extracts and 11-keto-ß-boswellic acids prevent type 1 and type 2 diabetes mellitus by suppressing the expression of proinflammatory cytokines

HPT Ammon - Phytomedicine, 2019 - Elsevier
Background Type 1 diabetes is an autoimmune disease directed to the pancreatic islets
where inflammation leads to the death of insulin-producing ß cells and insulin deficiency …

[HTML][HTML] Effect of Boswellia species on the metabolic syndrome: A review

D Mahdian, K Abbaszadeh-Goudarzi… - Iranian Journal of …, 2020 - ncbi.nlm.nih.gov
The metabolic syndrome, a cluster of metabolic disorders, includes abdominal obesity,
hypertension, dyslipidemia, and hyperglycemia leading to insulin resistance, development …

Protective effect of triterpenes against diabetes-induced β-cell damage: An overview of in vitro and in vivo studies

SE Mabhida, PV Dludla, R Johnson, M Ndlovu… - Pharmacological …, 2018 - Elsevier
Accumulative evidence shows that chronic hyperglycaemia is a major factor implicated in
the development of pancreatic β-cell dysfunction in diabetic patients. Furthermore, most of …