Synthesis of novel lupane triterpenoid-indazolone hybrids with oxime ester linkage

TS Khlebnicova, YA Piven, AV Baranovsky… - Steroids, 2017 - Elsevier
An efficient protocol for the synthesis of novel lupane triterpenoid-indazolone hybrids with
oxime ester linkage has been developed from naturally accessible precursor betulin. For the …

Regioselective construction of 1, 3-diaryl tetrahydroindazolones via the three-component reaction of 1, 3-cyclohexanediones, β-nitrostyrenes and arylhydrazines

T Wang, X Qing, C Dai, Z Su, C Wang - Organic & Biomolecular …, 2018 - pubs.rsc.org
1, 5, 6, 7-Tetrahydro-4H-indazol-4-one derivatives were successfully synthesized using a
one-pot three-component system that combines substituted β-nitrostyrenes, 1, 3 …

Discovery, structure–activity relationship studies, and anti-nociceptive effects of 1-phenyl-3, 6, 6-trimethyl-1, 5, 6, 7-tetrahydro-4H-indazol-4-one as novel opioid …

MF Cheng, LC Ou, SC Chen, WT Chang… - Bioorganic & Medicinal …, 2014 - Elsevier
The μ-opioid receptor (MOR) is the major opioid receptor targeted by most analgesics in
clinical use. However, the use of all known MOR agonists is associated with severe adverse …

Orthogonal Regioselective Synthesis of N‐Alkyl‐3‐substituted Tetrahydroindazolones

J Kim, H Song, SB Park - 2010 - Wiley Online Library
A divergent strategy for the regioselective and orthogonal synthesis of complementary
regioisomers of N‐alkyl‐3‐substituted‐tetrahydroindazolones 3 and 4 was achieved from …

Regioselective construction and screening of 1, 3-disubstituted tetrahydroindazolones in enantiomerically pure pairs

H Song, H Lee, J Kim, SB Park - ACS Combinatorial Science, 2012 - ACS Publications
In this paper, we describe a regioselective synthetic pathway for enantiopure 1, 3-
disubstituted tetrahydroindazolone derivatives via the condensation of 2-acylcyclohexane-1 …

Synthesis of fluorine-containing 6, 7-dihydrobenzisoxazolones from 2-(fluorobenzoyl) cyclohexane-1, 3-diones and their methyl enol ethers

TS Khlebnikova, YA Piveń, VG Isakova… - Chemistry of …, 2017 - Springer
Synthesis of fluorine-containing 6,7-dihydrobenzisoxazolones from 2-(fluorobenzoyl)cyclohexane-1,3-diones
and their methyl enol ethers | SpringerLink Skip to main content Advertisement SpringerLink …

Solid‐Phase Parallel Synthesis of a Tetrahydroindazolone Library Containing Three Unique Core Skeletons

J Kim, H Song, SB Park - Chemistry–An Asian Journal, 2011 - Wiley Online Library
We have developed a practical strategy for the regioselective synthesis of a 1‐(hetero) aryl‐
3‐substituted tetrahydroindazolone library. The condensation of in situ generated …

NMR and computational studies on tautomerism of 3-hydroxy-2-(2-thienylcarbonyl) cyclohex-2-en-1-one

GM Chans, EL Moyano, MT Baumgartner - Journal of Molecular Structure, 2014 - Elsevier
The tautomeric system of 3-hydroxy-2-(2-thienylcarbonyl) cyclohex-2-en-1-one 1 has been
investigated by NMR spectroscopy between 224 and 298 K. At all temperatures an …

2-Acylcycloalkanones in Organic Synthesis

VD Dyachenko, SM Sukach, AS Morkovnik - Russian Journal of Organic …, 2020 - Springer
2-Acylcycloalkanones in Organic Synthesis | Russian Journal of Organic Chemistry Skip to
main content SpringerLink Account Menu Find a journal Publish with us Track your …

Синтез фторсодержащих 6, 7-дигидробензизоксазолонов на основе 2-(фторбензоил) циклогексан-1, 3-дионов и их енольных метиловых эфиров

ТС Хлебникова, ЮА Пивень, ВГ Исакова… - Chemistry of …, 2017 - 5.179.29.131
Синтез фторсодержащих 6,7-дигидробензизоксазолонов на основе 2-(фторбе Page 1
1254 Лaтвийcкий инcтитут opгaничecкoгo cинтeзa Структурный фрагмент изоксазола …